Dermatitis is a term used to describe inflammation and damage of the layers of the skin. The causative agents are bacterial, fungal, mold, and parasitic infestations. Dermatitis has become problems in various regions in Indonesia and some other countries. Dermatitis often causes an unpleasant and disgusting feeling for the owner. Skin damage occurs to the dermis, thus showing clinical symptoms of hair loss, itching, redness of the skin, skin ulcers, and a bad smell of the animals. This study aims to determine the effect of giving honey from Trigona bees to improve the skin layer structure of patients with dermatitis in dogs and to see the development of skin lesions macroscopically. Research method: 10 dogs diagnosed with complex dermatitis were given fresh honey of 5 ml/day/dog. The treatment is given orally once a day for 35 days. Clinical observation of the wound healing process on the skin was observed every week for 5 weeks, and histopathological observations of the skin were carried out on the 0, 7, and 21 days. The results showed that giving fresh honey was able to repair skin damage with dermatitis lesions. It could be seen from the decrease in symptoms of erythema and the start of hair growth at the site of alopecia lesions. Histologically there was a decrease in the number of inflammatory cells (p<0.05) in the administration of honey. We concluded that Trigona's honey could be used as an herbal ingredient for treating dermatitis in dogs