Background: Methylcobalamin is essential vitamin required for DNA synthesis during cell division therefore maintain the architecture of nervous tissue distorted by soft metals such as Lithium Carbonate. Accurate documentation of the thickness cerebellar cortical thickness was required in subjects who were injected with methylcobalamin distorted by Lithium Carbonate. Aim: To provide data of cerebellar gray matter thickness distorted by Lithium Carbonate by the anti-oxidant effect of methylcobalamin. Methods: Fifteen albino rats were maintained on food and diet in Animal House of the Basic Medical Sciences Institute, JPMC Karachi for a period of 6 weeks. Results: The results obtained of the thickness of cerebellar gray matter distorted by Lithium Carbonate was restored by methylcobalamin in our study. Conclusion: To observe the neuroprotective effect of B12 on distorted cerebellar cortex treated by Lithium Carbonate. Keywords: Methylcobalamin, Lithium Carbonate, Gray Matter, Cerebellum

Objectives: To assess and compare the student’s attitude to professionalism among government and private medical colleges. Research question: Are there any differences in Professionalism attitudes of students studying in government and Private medical colleges of Pakistan? Hypothesis: Professionalism attitudes of Medical students studying in government and Private medical colleges do not differ from each other. Method: A government medical college of Sargodha & a Private medical college of Lahore were chosen for the study. Study was conducted from May to June 2019. 200 Final year MBBS students were given a questionnaire named Pakistani LAMPS validated through a pilot study. Non probability purposive sampling technique was used. We applied statistical test chi square used for analysis in SPSS 21 version. Results: Out of the study participants, there were 76(38%) were male &124(62%) female. The Pakistani LAMPS had an acceptable reliability index with a Cronbach’s alpha of 0.71. The items mean scores vary between (1.93+ 1.03 and 3.00+ SD 3.78, scale 1–5). The score was high significantly in Private medical college students (107/140) than Public medical college (95/140) with p value of 0.0001. Conclusion: The null hypothesis was rejected because the professionalism score of private medical college students was higher than that of government medical college students. Keywords: Professionalism, Attitudes, LAMPS Government, Private, Medical Education

<p><strong>Background and Objective:</strong> Pandemics like COVID-19 adversely affect children&rsquo;s behavior and psychological development by disrupting routine life activities. Children of healthcare workers are exposed additionally due to the fear of parental exposure to the virus. The objective of this study was to assess the perception of frontline healthcare workers (HCWs) regarding the psychological impact of the COVID-19 pandemic on their children. We also sought to identify the difference of the psychological impact on children of the male and female healthcare workers.<br /><strong>Methods:</strong> A survey questionnaire was developed comprising 10 questions about the perception of HCWs regarding the psychological impact of COVID-19 on their children. It was distributed both online and face to face among 150 healthcare professionals, working in training and non-training posts in 4 public and 5 nongovernment hospitals of Pakistan. The mean and standard deviation were calculated for each survey item using Statistical Package for the Social Sciences 26.0. Results: The response rate was 71.3% and majority (64.2%) of the healthcare professionals were &ge;30 years of age. Ninety-two HCWs (85.98%) either agreed or strongly agreed that the parental separation from their kids for long hours during the pandemic had a negative<br />psychological impact on their children. There was a significant difference in perceived psychological impact of COVID-19 on the children of male and female HCWs, with a mean survey score of 2.29 &plusmn; 1.82 and 1.69 &plusmn; 0.79, respectively (t = 2.29, p-value = 0.024).<br /><strong>Conclusion:</strong> Children of the healthcare workers experience more stress and anxiety because of long duty hours and working in high-risk settings. Continuous psychological support and counseling services may be adopted formally to prevent unforeseen adverse events or any long-term negative impact on their physical and mental health.</p>