The cytoplasmic polyadenylation element-binding (CPEB) protein family have demonstrated a crucial role for establishing synaptic plasticity and memory in model organisms. In this review, we outline evidence for CPEB3 as a crucial regulator of learning and memory, citing evidence from behavioral, electrophysiological and morphological studies. Subsequently, the regulatory role of CPEB3 is addressed in the context of the plasticity-related proteins, including AMPA and NMDA receptor subunits, actin, and the synaptic scaffolding protein PSD95. Finally, we delve into some of the more well-studied molecular mechanisms that guide the functionality of this dynamic regulator both during synaptic stimulation and in its basal state, including a variety of upstream regulators, post-translational modifications, and important structural domains that confer the unique properties of CPEB3. Collectively, this review offers a comprehensive view of the regulatory layers that allow a pathway for CPEB3’s maintenance of translational control that guides the necessary protein changes required for the establishment and maintenance of lasting synaptic plasticity and ultimately, long term learning and memory.

Control and monitor system of foamed cement mixing device are designed based on PLC and MCGS(Monitor and Control Generated System) configuration software, it realizes data collection and dynamic monitoring, data processing. Through the control system, it achieves automatic control to foamed cement mixing device. Experiments show the system has advantanges of high precision, reliability and good maintain.

This paper has done CAE analysis of hot stamping, and optimized the water-cooled system which takes the degree of uniform temperature of blank as the objective function of optimization. The aim is to find a method of optimizing hot stamping mold cooling system based on ANSYS Parametric Design Language (APDL) with ANSYS Mechanical/LS-DYNA software and lay the foundation for designing hot stamping mold. And the work mainly consists of three sections, building parametric finite element model, simulating the process of quenching and optimizing the location parameters and radiuses of each coolant duct. Finally, contrast the optimal result with the initial result and get the conclusion, and moreover, point out the future work.

PMAC motion controllers serve not only as a receiver of the orders from CNC systems of many kinds, but also as a controller of the motion of machine tools’ axles. With G83 as an example, a code commonly seen in the processing cycle of deep holes in CNC machining centers, it is advisable to come up with a method to write a special set of subprograms to invoke PMAC motion controllers with the application of G-code. Based on the method, case programing and machining simulation can be launched. Experiments justify that the method obtained can realize the compiling of fixed cycles with the use of G-code and, in turn, boast substantial significance in the development of open CNC processing machine tools.