Purpose Metabolic syndrome (Mets) is a pathological condition that includes many abnormal metabolic components and requires a simple detection method for rapid use in a large population. The aim of the study was to develop a diagnostic model for Mets in a Chinese population with noninvasive anthropometric and demographic predictors. Patients and methods Least absolute shrinkage and selection operator (LASSO) regression was used to screen predictors. A large sample from the China National Diabetes and Metabolic Disorders Survey (CNDMDS) was used to develop the model with logistic regression, and internal, internal-external and external validation were conducted to evaluate the model performance. A score calculator was developed to display the final model. Results We evaluated the discrimination and calibration of the model by receiver operator characteristic (ROC) curves and calibration curve analysis. The area under the ROC curves (AUCs) and the Brier score of the original model were 0.88 and 0.122, respectively. The mean AUCs and the mean Brier score of 10-fold cross validation were 0.879 and 0.122, respectively. The mean AUCs and the mean Brier score of internal–external validation were 0.878 and 0.121, respectively. The AUCs and Brier score of external validation were 0.862 and 0.133, respectively. Conclusions The model developed in this study has good discrimination and calibration performance. Its stability was proved by internal validation, external validation and internal-external validation. Then, this model has been displayed by a calculator which can exhibit the specific predictive probability for easy use in Chinese population.

Background Beekeeping and honey gathering are traditional forms of agricultural farming in China. However, only few studies have focused on the nutritional status and health level of this special occupational group. Objective By comparing the health status of apiculturists (beekeepers) and vegetable farmers in plain areas of Hubei Province, and analyzing the influence of dietary structure and intake on their nutritional level, this paper provides a scientific theoretical basis for the further development of health education and disease prevention for beekeepers. Methods From February to April 2016, 191/236 beekeepers (80.9% of the total beekeepers) with large-scale breeding (300-500 colonies) and 182 vegetable farmers in the same area were sampled by the cluster sampling method. Their nutrient composition was analyzed using a human body composition analyzer, dietary structure information was collected using the dietary frequency query method, and cognitive function was investigated. In addition, blood samples of both groups were collected. Results A total of 362 valid questionnaires (beekeepers/vegetable farmers: 185/177) were collected, with an effective response rate of 97.1% (362/373). Both beekeepers and vegetable farmers were overweight, and the beekeepers’ grip strength was much stronger than that of the vegetable farmers’ regardless of gender. The dietary structure of beekeepers is very unique: 29.7% (55/185) of beekeepers indicated consuming royal jelly regularly for more than 10 years. Their main foods are grain, cereals, and fresh vegetables; 68.1% (126/185) of the beekeepers never drank milk and other dairy products, and their overall nutrient intake is unbalanced. The average intake of cellulose in this group was also significantly higher than that in the epidemiological survey in the same sex and age group. The intake of vitamin A and selenium in the beekeepers group was significantly higher than that in the vegetable-farmers group (all P<.001). The blood indices of creatinine (P=.03) and blood copper (P<.001) in the beekeepers group were significantly higher than those in the vegetable-farmers group, and the total protein, albumin, calcium, sodium, potassium, phosphorus, folic acid, and vitamin B12 in the beekeepers group were significantly lower than those in the vegetable-farmers group (P<.03 for potassium and P<.001 for others). The total Mini-Mental State Examination (MMSE) score of the beekeepers group was 28.1, significantly higher (P=.006) than that of the vegetable-farmers group (23.3). Conclusions The beekeepers in this area have their special dietary structure, body nutrient level, and disease characteristics. The cognitive level of the beekeepers who regularly consume royal jelly is significantly higher than that of their peers. The chronic diseases of this special occupational group are closely related to their lifestyle and nutritional status, so more attention and in-depth studies are needed to improve the quality of life of this population.

BackgroundThere are no long-term (&gt;10 years) follow-up evaluations of the effects of handstand exercise or studies on the use of equipment for passive handstand exercise.ObjectiveTo report a 40-year follow-up investigation of a Chinese man who has been practicing passive handstand for 40 years.DesignThis observational investigation was conducted in Guizhou Province, China.ParticipantA (currently) 66-year-old Chinese man who had been practicing passive handstand exercise for 40 years was followed up.InterventionsPhysical and auxiliary examinations were carried out to determine the effects of long-term passive handstand exercise on the human body.Main MeasuresThe participant’s cerebrovascular, spinal health, mental health, and visual acuity as well as the presence of facial aging were examined.Key ResultsHis cerebral vessels were healthy, he appeared younger than his peers, his cervical spondylosis improved, and his mental state and cognitive function were good.ConclusionLong-term passive handstand exercise can promote cerebrovascular elasticity training and delay signs of aging. We recommend promoting this passive handstand exercise to the public.

UNSTRUCTURED Purpose: By comparing the health status of apiculturists (beekeepers) and vegetable farmers in plain areas of Hubei Province, and analyzing the influence of dietary structure and intake on their nutritional level, this paper provides a scientific theoretical basis for the further development of health education and disease prevention for beekeepers. Method: A total of 191 beekeepers (81% of the total beekeepers) with large scale breeding (300-500 colonies) and 182 vegetable farmers in the same area were sampled by cluster sampling method. Nutrient composition was analyzed by human body composition analyzer, dietary frequency query method was used to collect dietary structure information, and cognitive function was investigated and blood samples were collected. Results: 362 valid questionnaires (beekeepers/vegetable farmers:185/177) were collected, with an effective response rate of 97.1%. Both the beekeepers and the vegetable farmers were overweight, and the bee-farmers' grip strength was much stronger than that of the vegetable farmers regardless of gender. The dietary structure of beekeepers is very special:(1) 29.7% of beekeepers insist on eating royal jelly regularly for more than 10 years; (2) the main food is grain, cereals and fresh vegetables, among which 68.1% of the farmers never drink milk and other dairy products, and the nutrient intake is unbalanced; The average intake of cellulose in this group was also significantly higher than that in the epidemiological survey of the same sex and age group. The intake of vitamin A and selenium in beekeepers group was significantly higher than that in vegetable-farmers group (all P <0.05). (3) The blood indexes of creatinine, uric acid and blood copper in beekeepers group were significantly higher than those in vegetable-farmers group, and the total protein, albumin, calcium, sodium, potassium, phosphorus, folic acid and vitamin B12 in beekeepers group were significantly lower than those in vegetable-farmers group. (4) The total Mini-mental State Examination (MMSE) score of the beekeepers group was 28.1, significantly higher than that of the vegetable-farmers group (23.3). Conclusion: The beekeepers in this area have their special dietary structure, body nutrient level and disease characteristics. The cognitive level of the beekeepers who regularly eat royal jelly is significantly higher than that of their peers. The chronic diseases of this special occupational group are closely related to their life style and nutritional status, so more attention and in-depth study are needed to improve the quality of life of this group.