Aim Frontline nurses’ willingness to work has significant implications for maintaining workforce stability and quality of care during the COVID‐19 pandemic; however, few studies have investigated their willingness and the corresponding reasons. This study aims to examine frontline nurses’ willingness to work, identify its predictors and explore its corresponding reasons. Design A mixed‐methods design was conducted. Methods Based on a multilevel behavioural‐diagnostic model, a questionnaire survey was used to collect quantitative and qualitative data concurrently from 13 February to 24 February 2020 to explore frontline nurses’ willingness to work and the corresponding reasons in two hospitals in Wuhan, China. One was a designated hospital which only received COVID‐19 patients, and the other was built up temporarily for COVID‐19 patients. Results Of the 2014 participants, most (n = 1950, 96.8%) indicated their willingness to work, and a few (n = 64, 3.2%) expressed their unwillingness. Binary logistic regression analysis identified five predictors of participants’ willingness to work, including monthly family income, average working hours per shift, belief in their colleagues’ preparedness, belief in their hospitals’ preparedness and levels of depression. These indicators explained 27% of the variance (p < .05). Frontline nurses’ willingness to work mainly arose from professional commitment, patriotism and faith, while unwillingness to do so primarily stemmed from safety concerns and family responsibility. Conclusion Most frontline nurses were willing to work and showed great professional commitment. Impact Professional commitment and patriotism were two important individual‐level factors affecting frontline nurses’ willingness to work during a pandemic. Strategies should be implemented, such as appreciating and acknowledging their contribution, rewarding their valuable work, arranging reasonable working hours, enhancing colleagues’ and hospitals’ preparedness, and providing emotional support. Moreover, adequate personal protective equipment, self‐protection training and social support should be ensured to address frontline nurses’ safety concerns and family responsibility.

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Aim To explore the mediating role of fear and resilience on the relationship between clinical nurses' reporting of skin lesions and their anxiety and depression during the coronavirus disease 2019 (COVID‐19) pandemic. Background Prolonged personal protective equipment wearing may cause severe skin lesions among clinical nurses. The possible relationship between clinical nurses' reporting of skin lesions and their anxiety and depression remains unknown. Moreover, little is known about what factors could mediate such a relationship. Methods This is a cross‐sectional online survey. CHERRIES was used to report results. Results Of 2014 participants, 94.8% ( n = 1910) reported skin lesions. Skin lesions were positively related to anxiety ( p < .001, β = .228, SE = .099) and depression ( p < .001, β = .187, SE = .093). Fear activated while resilience buffered the relationship between clinical nurses' reporting of skin lesions and anxiety and between skin lesions and depression. Conclusion Reduced fear and enhanced resilience level were related to decreased levels of anxiety and depression among clinical nurses. Implications for nursing management Nurse managers should evaluate the occurrence and severity of clinical nurses' skin lesions, arrange reasonable working duration to relieve skin lesions, provide appropriate psychological support to reduce clinical nurses' fear and implement various strategies to enhance their resilience, thereby decreasing their anxiety and depression. Clinical trial registration number: ChiCTR2000030290

Electrochemical aptasensing systems have been developed for screening low-abundance disease-related proteins, but most involve mutiple washings and multi-step separation during the measurement, and thus are disadvantageous for routine use. In...