Local climates are responding to global warming differently, and the changes in rainstorms in mountainous areas of Southwest China are of particular interest. This study, using monthly NCEP/NCAR reanalysis and daily precipitation observation of 90 meteorological stations from 1961 to 2021, analyzed the temporal and spatial variation characteristics of rainstorms and floods in Southwest China and their relationship with atmospheric circulations. The results led us to the following five conclusions: (1) Rainstorms and floods in southwest China mainly occur from June to August, during which time July has the most weather events, followed by August. (2) The southwest of Guizhou province, the southern edge of Yunnan province, and regions from the east of the Sichuan Basin to the north of Guizhou have experienced more rainstorms and floods, while the northwest regions of Southwest China have had fewer. (3) Over the last 61 years, rainstorms and floods have exhibited an overall rising trend, especially in the last 10 years. The year 2012 was an abrupt inflection point in rainstorms and floods in Southwest China, from low to high frequency, while the correlation coefficient between rainstorms and floods and the global surface temperature is above the 95% significance level. (4) Rainstorms and floods exhibit changes at periods of 8 years, 16 years, and 31 years. (5) Rainstorms and floods show a good correlation with multiple variables, such as South Asian high-pressure systems west of 90°E, the upper trough front, the northwest side of the western Pacific subtropical high, and the convergence of warm and wet air in the middle and lower layers with cold air on the ground.