A novel series of composite hydrogels, built from the three components 1), hyaluronic acid methacryloyl (HAMA); 2), gelatin methacryloyl (GelMA), and 3), extracellular cartilage matrix (ECM), was prepared and studied regarding the possible utility in the surgical repair of damaged (perforated) tympanic membrane (TM). Noteworthy is component 3), which was harvested from the ribs of α-1,3-galactosidyltransferase-knockout (α-1,3 GalT-KO) pigs. The absence of α-1,3-galactosyl glycoprotein is hypothesized to prevent rejection due to foreign-body immunogenicity. The composite hydrogels were characterized by various aspects, using a variety of physicochemical techniques: aqueous swelling, structural degradation, behavior under compression, and morphology, e.g., in vitro biocompatibility was assessed by the CCK-8 and live–dead assays and through cytoskeleton staining/microscopy. Alcian blue staining and real-time PCR (RT-PCR) were performed to examine the chondrogenic induction potential of the hydrogels. Moreover, a rat TM defect model was used to evaluate the in vivo performance of the hydrogels in this particular application. Taken together, the results from this study are surprising and promising. Much further development work will be required to make the material ready for surgical use.

Student information management is not only the basis of realizing efficient education and teaching management in Colleges and universities, but also an important link. However, in recent years, with the popular development of higher education, the number of students is further expanded, the number of students has increased a lot compared with the past, and the work of student information management has become increasingly heavy, which has brought new challenges to student information management. This requires managers (class teachers, class cadres) to update the concept of student management, innovate the student management mode, and use modern information technology to manage class affairs and student information. This topic is based on the realization of the standardization, digitization and automation of student information management, which can help class teachers and class cadres save manpower, material resources and financial resources, further improve the efficiency and accuracy of class information management in sports colleges and universities, strive to improve the scientific level of student information management, and provide a platform for students to broaden their horizons and actively participate in school activities. In this paper, through the design and development of sports information management system, and through the function and performance test, it is found that the system can meet the needs of colleges and universities, which simulates the results of 200 users’ concurrent number of operating system. The user concurrent number is the largest user concurrent number index of non functional requirements of the system, and the corresponding test items have passed the performance test requirements.

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