In the present study, we sequenced and analyzed the complete genomes of the goose parvovirus (GPV) and the duck parvovirus (MDPV) isolates derived from a co-infected dead Muscovy duckling without any symptoms of other emerging Muscovy duck diseases. The genomic organization and sequences analysis indicates that the size of the full-length inverted terminal repeats regions determines the genomic length of GPV and MDPV, with which the lengths of the non-structural protein and capsid proteins coding region were highly conserved. According to the phylogenetic analysis, there are two genotypes of duck parvoviruses co-circulating in Muscovy ducks in China INTRODUTIONAnseriform dependoparvovirus 1 belonging to the family Parvoviridae that classified into two subfamilies (Densovirinae and Parvovirinae), which are further classified in thirteen generas (5 within Densovirinae and 8 within Parvovirinae). Anseriform dependoparvovirus 1 now have two groups that include goose parvovirus (GPV) and the duck parvovirus (MDPV). The MDPV is closely related to the GPV based on the southern hybridization assays and shared more than 80.0% sequence identity with GPV. GPV can cause highly contagious and fatal disease in goslings and Muscovy ducklings; whereas MDPV only cause disease with Muscovy ducklings [1,2] . The MDPV and GPV contain single-stranded DNA genome of approximately 5.1-kb in length, sharing closely related in genome and neutralization. The genome contains two major open reading frames (ORFs). The left ORF1 encodes the non-structural protein (NS) involved in viral replication, and the right ORF2 encodes the viral capsid proteins VP1, VP2 and VP3. The VP2 and VP3 shared the same C-terminal of the VP1, which were produced by alternate splicing [3,4] . The MDPV and GPV were reported once epidemic in many Muscovy duck breeding regions, such as Hungary, China, Japan, Thailand, France, and the USA. Though the attenuated vaccine against MDPV and GPV were used İletişim (Correspondence) +86 591 87572396 (Yu Huang); +86 591 83789492 (Kai-hui Hu)
In the present study, we sequenced and analyzed the complete genome of goose parvovirus isolates derived from Anser cygnoides. Comparing with other GPV isolates, the results indicated that the event may cause by GPV direct infection to Anser cygnoides. These findings suggest that the Anser cygnoides could serve as a potential host for GPV and enable us to understand the molecular characteristics and evolutionary diversity of GPV. Keywords: Goose parvovirus, Anser cygnoides, Genome, Analysis Çin'de Anser cygnoides'ten Izole Edilen Kaz Parvovirusu'nun Tam Genomik Dizilimi ÖzetBu çalışmada, Anser cygnoides'ten elde edilen kaz parvovirusu genomunun dizilimi yapıldı ve analiz edildi. Diğer GPV izolatlarıyla kıyaslandığında, sonuçlar olayın doğrudan Anser cygnoides'e bağlı bir GPV enfeksiyonuna bağlı olabileceğini gösterdi. Bu bulgulara göre, Anser cygnoides'in GPV için potansiyel bir konakçı (ev sahibi) olarak hizmet edebildiği ve GPV'nin moleküler özelliklerinin ve evrimsel çeşitliliğinin anlaşılmasını sağlayabildiği kanısına varıldı.
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