Increasing economic globalization and the diffusion of political democracy are arguably the two most important characteristics of contemporary international political economy. As a salient dimension of globalization, foreign direct investment (FDI) inflows have grown faster than world income since the 1960s, multinational enterprises (MNEs) now account for about 70 percent of world trade, and the sales of their foreign affiliates have exceeded total global exports. 1 Foreign production capital has dispersed to almost all developing countries since the 1980s, and the number of foreign affiliates located in developing economies has reached 129,771, compared with 93,628 in the developed world. 2 Paralleling this economic structural change is the spread of liberal or representative democracy. A growing number of less-developed countries (LDCs) have experienced increased political participation, open competition for elected office, and expanding civil society. The proportion of democratic and partially democratic countries rose from about 31 percent in 1975 to about 73 percent in 1995. 3 The flood of FDI and the diffusion of democratic governance have come to an inevitable encounter. While the effect of FDI on democracy has long attracted both scholarly attention and public interest, 4 the effect of democracy on FDI is surprisingly understudied and poorly understood. Explaining the effect of democratic institutions on FDI, however, has clear significance for both theory and policy. ManyWe thank

In 2015, the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) published updated standards and guidelines for the clinical interpretation of sequence variants with respect to human diseases on the basis of 28 criteria. However, variability between individual interpreters can be extensive because of reasons such as the different understandings of these guidelines and the lack of standard algorithms for implementing them, yet computational tools for semi-automated variant interpretation are not available. To address these problems, we propose a suite of methods for implementing these criteria and have developed a tool called InterVar to help human reviewers interpret the clinical significance of variants. InterVar can take a pre-annotated or VCF file as input and generate automated interpretation on 18 criteria. Furthermore, we have developed a companion web server, wInterVar, to enable user-friendly variant interpretation with an automated interpretation step and a manual adjustment step. These tools are especially useful for addressing severe congenital or very early-onset developmental disorders with high penetrance. Using results from a few published sequencing studies, we demonstrate the utility of InterVar in significantly reducing the time to interpret the clinical significance of sequence variants.

The efficient use of solar energy has received wide interest due to increasing energy and environmental concerns. A potential means in chemistry is sunlight-driven catalytic reactions. We report here on the direct harvesting of visible-to-near-infrared light for chemical reactions by use of plasmonic Au-Pd nanostructures. The intimate integration of plasmonic Au nanorods with catalytic Pd nanoparticles through seeded growth enabled efficient light harvesting for catalytic reactions on the nanostructures. Upon plasmon excitation, catalytic reactions were induced and accelerated through both plasmonic photocatalysis and photothermal conversion. Under the illumination of an 809 nm laser at 1.68 W, the yield of the Suzuki coupling reaction was ~2 times that obtained when the reaction was thermally heated to the same temperature. Moreover, the yield was also ~2 times that obtained from Au-TiOx-Pd nanostructures under the same laser illumination, where a 25-nm-thick TiOx shell was introduced to prevent the photocatalysis process. This is a more direct comparison between the effect of joint plasmonic photocatalysis and photothermal conversion with that of sole photothermal conversion. The contribution of plasmonic photocatalysis became larger when the laser illumination was at the plasmon resonance wavelength. It increased when the power of the incident laser at the plasmon resonance was raised. Differently sized Au-Pd nanostructures were further designed and mixed together to make the mixture light-responsive over the visible to near-infrared region. In the presence of the mixture, the reactions were completed within 2 h under sunlight, while almost no reactions occurred in the dark.

Light-driven phenomena both in living systems and nonliving materials have enabled truly fascinating and incredible dynamic architectures with terrific forms and functions. Recently, liquid crystalline materials endowed with photoresponsive capability have emerged as enticing systems. In this Review, we focus on the developments of light-driven liquid crystalline materials containing photochromic components over the past decade. Design and synthesis of photochromic liquid crystals (LCs), photoinduced phase transitions in LC, and photoalignment and photoorientation of LCs have been covered. Photomodulation of pitch, polarization, lattice constant and handedness inversion of chiral LCs is discussed. Light-driven phenomena and properties of liquid crystalline polymers, elastomers, and networks have also been analyzed. The applications of photoinduced phase transitions, photoalignment, photomodulation of chiral LCs, and photomobile polymers have been highlighted wherever appropriate. The combination of photochromism, liquid crystallinity, and fabrication techniques has enabled some fascinating functional materials which can be driven by ultraviolet, visible, and infrared light irradiation. Nanoscale particles have been incorporated to widen and diversify the scope of the light-driven liquid crystalline materials. The developed materials possess huge potential for applications in optics, photonics, adaptive materials, nanotechnology, etc. The challenges and opportunities in this area are discussed at the end of the Review.

This article studies the various mechanisms by which democracy affects transnational terrorism. New theoretical mechanisms are identified that either complement or encompass existing arguments. Different effects of democracy on transnational terrorism are assessed for a sample of about 119 countries from 1975 to 1997. Results show that democratic participation reduces transnational terrorist incidents in a country, while government constraints increase the number of those incidents, subsuming the effect of press freedom. The proportional representation system experiences fewer transnational terrorist incidents than either the majoritarian or the mixed system.