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In this paper, for controlling the spread of plant diseases, a nonautonomous SEIS (Susceptible → Exposed → Infectious → Susceptible) epidemic model with a general nonlinear incidence rate and time-varying impulsive control strategy is proposed and investigated. This novel model could result in an objective criterion on how to control plant disease transmission by replanting of healthy plants and removal of infected plants. Using the method of small amplitude perturbation, the sufficient conditions under which guarantee the globally attractive of the disease-free periodic solution and the permanence of the disease are obtained, that is, the disease dies out if 1 1 R < , otherwise, the disease persists if 2 1 R > .