In summary, our results suggested that VEGF variants (-2578C/A, -1154G/A, -634G/C, +963G/A) were involved in the susceptibility of TOF. However, validation of our study needs further study in various ethnics to reveal the functional relationship between VEGF polymorphisms and TOF risk, which may contribute to diagnosis and therapy of TOF.

The splitter is an important component of water-based cooling systems used to extract heat from computer boards. In the present study, the flow characteristics of a 16-splitter structure were numerically simulated and compared with experimental results to verify the reliability of the numerical simulation method. Accordingly, the concept of splitter structural coefficients was proposed. Based on the results of this study, we recommend a selection range of 5 ≤ k ≤ 6 for the structure factor k of the splitter; after optimization, the maximum deviation of the splitter outlet flow was reduced from the original value of 100% to 8.3%.

To investigate the fouling characteristics of the composite insulator surface under the salt fog environment, the FXBW-110/120-2 composite insulator was taken as the research object. Based on the field-induced charge mechanism, the multi-physical field coupling software COMSOL was used to numerically simulate the fouling characteristics, explored the calculation method of ESDD, and demonstrated its rationality. Based on this method, the pollution characteristics of the composite insulator under the pollution fog environment were studied, and the influence of wind speed, droplet size, and voltage type on the pollution characteristics of the composite insulator was analyzed. The results showed that: with the increase in wind speed, the amount of accumulated pollution of insulator increases in the range of droplet size, and the relationship between wind speed and accumulated pollution is approximately linear; at the same wind speed, the amount of accumulated pollution increases with the increase of droplet size under the action of DC voltage; when there is no voltage, the amount of dirt on the upper surface of the insulator is more than that on the lower surface, while it is the opposite under DC voltage.

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