The development of efficient and low-cost catalytic systems is important for the replacement of the robust noble metal complexes. A highly efficient, stable, phosphine-free, and easy-tosynthesize iron catalyst system for the reduction of CO 2 , hydrogenocarbonate, and carbonate in pure water is reported. In the presence of the bifunctional cyclopentadienone iron tricarbonyl Fe4a− d, the hydrogenation of carbonic derivatives proceeds in good yields with good catalyst productivity. Turnover numbers (TON) of up to 3343, 4234, and 40 for the hydrogenation of CO 2 , hydrogenocarbonate, and carbonate, respectively, to formate in pure water were achieved. For the CO 2 hydrogenation, a base was required, and triethanolamine emerged as the best one. DFT calculations rationalized the mechanism as well as the better performance of triethanolamine as a base.
A transition-metal
frustrated Lewis pair approach has been envisaged
to enhance the catalytic activity of tricarbonyl phosphine-free iron
complexes in reduction of amines. A new cyclopentadienyl iron(II)
tricarbonyl complex has been isolated, fully characterized, and applied
in hydrogenation. This phosphine-free iron complex is the first Earth-abundant
metal complex that is able to catalyze chemoselective reductive alkylation
of various functionalized amines with functionalized aldehydes. Such
selectivity and functionality tolerance (alkenes, esters, ketones,
acetals, unprotected hydroxyl groups, and phosphines) have been demonstrated
also for the first time at room temperature with an Earth-abundant
metal complex. This alkylation reaction was also performed without
any preliminary condensation and generated only water as a byproduct.
The resulting amines provided rapid access to potential building blocks,
metal ligands, or drugs. Density functional theory calculations highlighted
first that the formation of the 16 electron species, via the activation
of the tricarbonyl complex Fe3, was facilitated and,
second, that the hydrogen cleavage did not follow the same pathway
as bond breaking, usually described with the known cyclopentadienone
iron tricarbonyl complexes (Fe1 and Fe4).
These calculations highlighted that the new complex Fe3 does not behave as a bifunctional catalyst, in contrast to its former
congeners.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.