Porphyromonas gingivalis, the major human pathogen associated to periodontal diseases, utilizes the Bacteroidetes-specific type IX secretion system (T9SS) to export virulence factors. PorE is a periplasmic multi-domain lipoprotein associated to the outer membrane that was recently identified as essential for T9SS function. Little is known on T9SS at the structural level, and in particular its interaction with peptidoglycan. This prompted us to carry out structural studies on PorE full length as well as on its four isolated domains. Here we report the crystal structure of the C-terminal OmpA_C-like putative peptidoglycan-binding domain at 1.55 Å resolution. An electron density volume was identified in the protein cleft, making it possible to build a naturally-occurring peptidoglycan fragment. This result suggests that PorE interacts with peptidoglycan and that PorE could anchor T9SS to the cell wall.

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is a traditional herbal medicine in Vietnam. Previous investigations reported mainly compounds and bioactivities of roots, stems, and leaves while there is limited information about those of fruits. This study aims to reveal the difference in the chemical profile of defatted peel (DP) and nondefatted peel (NDP) methanolic extracts of P. trimera using colorimetric reactions and liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) analysis. We also showed the potential antibacterial activity of two extracts against clinically isolated bacteria strains including P. aeruginosa, Salmonella sp., and S. aureus with the MIC values < 100 μg/mL. This preliminary result proves the traditional usage of this herbal medicine and can be helpful for further investigation on the isolation and identification of the new compounds in P. trimera peels.

Oily waste-water is generated in many industrial processes, such as oil refining, oil storage, exploration, transportation, washing ... Oily waste water poses a great problem with water environment, ecosystem and human health. Nowadays, application of microbial biofilm for the removal of oil and derivatives from contaminated environments has received much attention. Microbial biofilms are defined as complex coherent structure of cells and cellular products, which are attached on solid surface. In biofilm structure, microorganisms increase their ability to grow and survive in changing environmental conditions and increase their access to absorb substrates or nutrients. This study focused on the degradation of hydrocarbon components contaminated in oil polluted waste water by biofilm formed by a mixture of bacterial and yeast strains isolated from oil contaminated water in Viet Nam attached on coconut fiber carriers in 2000 liter system. As the results, biofilm attached on coir carrier could degrade 62% after 5 days and 99,9% after 7 days of the total amount of oil with the initial concentration of 31.950 mg/l. Phenol and polycyclic aromatic hydrocarbons (PAHs) also were degraded up to 99.9% phenol and more than 94,8%PAHs in oily wastewater. This result gave hint to develop new method to treat petroleum oil contaminated water in Vietnam.

Vietnam has a variety of pig genetic resources, which has not been well studied. Traditional Vietnamese pig breeds are generally characterized with high fat content and slow growth rate. Therefore, their productivity could not be compared to those of Western breeds such as Landrace or Large White, which was very important for Vietnamese farmers during the initial years of economic

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