BackgroundThe calcium intake on the diet below normal daily requirements is related with low levels of vitamin D. The available scientific evidence supports a key role of calcium and vitamin D in skeletal health. We analyzed this relationship in healthy colombian population and describe this association.ObjectivesThe main objetive is to Assess the prevalence of hypovitaminosis D and the relationship with the daily calcium intake in a healthy Colombian population. Furthermore it is crucial to estimate the impact of key mineral elements such as Calcium and Vitamin D in bone health.MethodsIn a prospective cohort of general population we measure the prevalence of hypovitaminosis D and the calcium intake, (mg/dl) following demographic, antropomethric, biochemical characteristics and sun exposure of the population evaluated. We used a model of multiple regresion to predict the levels of vitamin D regarding the factors analysed. We excluded patients with secondary conditions that affect the absorption of calcium and vitamin D.ResultsWe included 97 patients, average age 23 yrs, 61% women, average weight 65 kg, Height 165 cm, average BMI 22.8. The calcium intake was 393,7 mg/d, levels of vitamin D were 23.71. We identified hypovitaminosis D in 87% of the patients, 24.7% had vitamin D defficiency and 63% had insufficiency (Figure 1, Levels of Vitamin D in the population study).The concentration of Vitamin D was calculated in quadratic function, for the relationship between sex, sun exposure and habitual calcium intake. (R:>90%).ConclusionsWe found a strong relationship between low calcium intake and hypovitaminosis D in the study group. In a healthy colombian population we saw an important low intake of calcium on the diet and high prevalence of Hypovitaminosis D. These findings have enormous impact on public health policy in our country. Effective and imperative strategies are required to prevent future complications such as Osteoporosis and secondary fractures.ReferencesCatharine-Ross A., et al. The 2011 report on dietary references intake for calcium and vitamin D from the Institute of Medicine. What clinicians need to know. JCEM 2011;96:53–58Disclosure of InterestNone declared

Background: Daily dietary calcium intake below the requirements has been related to lowlevels of vitamin D (Vit-D) and osteoarticular diseases. Objective: To determine the prevalence of Vit-D deficiency in the general population living in Bogotá, its relationship to dietary calcium intake, and the influence of socio-demographic factors and sunlight exposure. Materials and methods: In a pro-spective cohort of the general population (randomly selected), excluding individuals with conditions affecting calcium absorption or adequate Vit-D action, the prevalence of hypovitaminosis D (95 % ci) and regular consumption of calcium (rci, mg/day) is measured according to socio-demographic, anthropometric, biochemical, and sunlight exposure variables. A multiple regression model is implemented (no intercept) to predict Vit-D concentration based on the factors described. Results: Ninety-seven patients are included, 61 % of which are women, with a median age of 23 years, a weight of 65 kg (iqr: 55.2–70.5), a height of 165 cm ± 8.9, and bmi of 22.8 kg/m2 (iqr: 21.2–25.2). The rci was 393.7 mg/day, less than the benchmark for Colombian adults (p < 0.001); serum calcium concentration was 9.7 mg/dL. The mean Vit-D concentration (95 % ci) was 23.7 ng/mL (22.6–24.7); hypovitaminosis D was identified in 87 % of the sample (80.6–94.7 %), 24.7 % were classified as poor (15.6–33.8 %) and 62.9 % as insufficient (52.8–73 %). Vit-D concentration was predicted in a quadratic function by the interaction between sex, sunlight exposure, and rci (R2 > 90 %). Conclusion: The suspected high prevalence of Vit-D deficiency is confirmed in the general Colombian adult population as a result of low dietary calcium intake, demographic factors, and sunlight exposure.

BackgroundVitamin D is a steroid hormone with pleiotropic effects on physiological processes. Among others, immune system regulation and their analogues prevent symptom development of autoimmune diseases such as SLE. A previous research in a colombian clinic found a prevalence of hipovitaminosis D of 87% in healthy population, but hypovitaminosis D is higher in SLE patients than healthy controls.ObjectivesTo establish the prevalence of hypovitaminosis D in patients with SLE and relationship with SLEDAI – 2K.MethodsA cross sectional study was carried out. 80 medical records with a diagnoses of SLE o CIE-10 M30-M36 were identified and we included patients>18 years of age who meet at least 4 of the 11 criteria to diagnoses of SLE for medical record. The analysis included means, DS and Kruskall Wallis with p-value<0.05.ResultsThe majority of patients are women (94%), with an average age of 39.9 years, married (41%), with secondary education (56.7%) and different occupations. It was found that the patients with higher activity, had lower vitamin D levels. Additionally, if the patient had lupus nephritis, vitamin D levels decreased even more.Abstract AB0618 – Figure 1ConclusionsPatients with active systemic lupus Erythematosus, (SLE) have hypovitaminosis D more frequently and we noticed that patients with renal involvement have the lowest levels of vitamin D, which justifies a later analysis.References[1] American College of Rheumatology. Guidelines for referral and management of systemic lupus erythematosus in adults. Arthritis Rheum. 1999Sep;42(9):1785–96.[2] Simioni J, Heimovski F, Skare T. On lupus, vitamin D and leukopenia. 2016;56(3):206–211.[3] Guzman R.A, Piñeros L.G, Theran A, Flechas J, Mejía M. AB0795 Hypovitaminosis D and Calcium Intake of Adult Population in Bogota (DICAVITD). Ann Rheum Dis2016;75:1175–1176.[4] Alele J., et al. Autoimmun Rev2010;9:137–39.[5] Dall, era M., et al. in Kelley&Firestein,s Textbook of Rheumatology. 10th Ed, Elsevier; Philadelphia 2017; 1368–89.Disclosure of InterestNone declared