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A series of p-substituted thiazolyl styryl ketones were synthesized by the Claisen -Schmidt condensation of various substituted benzaldehydes with 5-acetyl-2,4-dimethyl thiazole. The IR spectra for all the chalcones were recorded and effect of substituent on the carbonyl and C=N stretching frequencies  are analyzed.

A newchalcone is derived from the Claisen-Schmidt condensation of and 4-methylbenzaldehyde with 5-Acetyl-2, 4-dimethyl thiazole in basic medium .The newly synthesized chalcone is characterized UV, IR, and NMR spectral techniques. DFT studies have also been carried out.

The main objective of this work was to prepare and to evaluate the antibacterial and anti fungal activity of 2-Pyridinealdazine.This azine is screened for its antimicrobial activity against both gram positive and gram negative bacterial and fungal strains like fungal strains Aspergillus flavus, Aspergillus niger, Fusarium oxysporum, Penicillium chrysogenum,Trichoderma viride. 2-Pyridinealdazine was found to be effective inhibitor of all pathogenic strains with the inhibition zone ranging from 10 to 30mm.