There is no consensus on applying alloplasty in the care of strangulated complicated ventral hernias. Aim: to enhance the effectiveness of alloplasty in the management of strangulated complicated ventral hernias. Materials and methods. The results were obtained from a retrospective clinical analysis of the surgical treatment of 146 patients with diagnosis of strangulated complicated ventral hernias, who underwent urgent surgical operations by an open method with the use of alloplasty at the surgical department of the 1st Municipal Clinical Hospital in Poltava for the period from 2010 to 2020. There were 114 women (78.1%) and 32 men (21.9%). The age of patients ranged from 21 to 85 years (average age was 62±3.2 years). Postoperative hernias prevailed were more prevalent (n=117, 80.1%), recurrent hernias were found in 31 (21.2%) patients. Median localization of the defect (M) was found in 134 patients (91.8%), lateral defects (L) was diagnosed in 12 patients (8.2%). The following alloplasty techniques were applied: "onlay" for in 2 patients (1.4%), "sublay" for 116 (79.5%), "sublay-inlay" for 18 (12.3%), "inlay" for 3 (2.1%), separation of anatomical components was performed in 7 (4.7%) cases. Results. In the early postoperative period, local complications were observed in 14 (9.6%) cases. General postoperative complications were noted in 11 (7.5%) cases; 2 (1.4%) patients died. In the remote period, local complications were recorded in 8 patients (5.5%). Conclusion. Performing alloplasty in patients with strangulated complicated ventral hernias enables to reduce the number of complications and improve the results of surgical outcomes.