A field experiment was carried out at the present experiment entitled “Productivity and profitability of sprouting broccoli (Brassica oleracea var. italica Plenck) under different major nutrient management with organic sources” was conducted at Vegetable farm, Chandra Shekhar Azad University Of Agriculture And Technology, Kanpur during rabi season 2021-22.The experiment consists of twenty-four treatment combinations of six sources of organic manure and four levels of major nutrients. The experiment was laid out in factorial RBD design and replicated three times. Palam samridhi variety of broccoli was transplanted at spacing of 45x45 cm. Results of the experiment revealed that the total head yield (q/ha) was significantly higher under M6 (FYM 20 t +Vermicompost 5 t  + Poultry manure  5 t  ha-1 ) source of manure which was at par application of M4 (Vermicompost 5 t ha-1) whereas in case of major nutrients it was significantly higher under application of (140:80:80 kg NPK ha-1) but it was at par with (120:60:60 kg NPK ha-1) and significantly superior to rest sources of organic manure. Maximum cost of cultivation, gross return as well as net return was associated with F3 (140:80:80 kg NPK ha-1) level of major nutrient but higher benefit cost ratio was noted under M3 (Poultry manure 5t/ha) source of manure and combination of M6 sources of manure along with F2 level of major nutrient fetches maximum net return of 9.71 which was followed by rest treatment combinations.