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Objectives: Currently there is no formal HTA agency in Russia, although the need for HTA as an evidence tool for policy makers is increasing due to budget constraints. However, there are HTA bodies which to some extent influence decison makers through publications of pharmacoeconomic studies. The objective of the present study was to gain insights into the current activities of existing HTA organizations and research trends in developing HTA in Russia. MethOds: A manual search of four Russian HTA organizations' websites was conducted to find pharmacoeconomic assessments published from 1998 onwards. Per agency, all relevant reports were categorized by therapeutic area and publication date. Any revealed patterns in the HTA topics were in-depth analyzed and compared with the World Health Organization (WHO) country profile of Russia. Results: In total, 180 pharmacoeconomic assessments published by four Russian HTA organizations were identified. Overall, the majority of studies were performed in cardiovascular (n= 45; 25%) and oncology (n= 32; 18%) disease areas, which are according to the WHO, the two leading causes of death, both in Russia and globally. The total number of pharmacoeconomic publications per year has been constantly increasing from one study in 1998 to 26 in 2009, however with fewer reports published in 2010-2013 (32 HTAs in three years). When reported, the potential willingness-to-pay (WTP) threshold for cost-effectiveness was suggested to be 3*Gross Domestic Product (GDP) per capita as recommended by WHO, which equals to approximately 30,000 euro per Quality Adjusted Life Year (QALY) gained. cOnclusiOns: Although formally Russia does not have a transparent HTA based reimbursement process, existing HTA organizations are constantly developing and gaining HTA experience by conducting assessments in the therapeutic areas with the highest burden on Russian population. These areas of interest, as well as an approach to define WTP threshold, match with WHO data and recommendations.

A127conditions were more frequent in parents with NEs related to work or friends. CONCLUSIONS: PWH with one NE were more likely to report other NEs. PWH/parents with NEs reported greater social worker involvement and treatment for psychological conditions. Further studies are needed to assess temporal relationships between NEs and HTC visits/advice, and support the relevance of timely social work and psychological counselling in comprehensive care.