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Synthesis and Cyclization of 1-(N-Nitroamidino)thioureas to 2,4-Diaminothiazoles.-Reaction of nitroguanidine (I) with isothiocyanates in the presence of powdered KOH provides 1-(N-nitroamidino)thioureas (III) which react with phenacyl bromides to give unexpectedly 2,4-diaminothiazoles (V) in high yield. -(BINU, R.; THOMAS, K. K.; JENARDANAN, G. C.; RAJASEKHARAN, K. N.; Org. Prep. Proced. Int. 30 (1998) 1, 93-96; Dep.

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Synthesis of 2,4-Diamino-5-cinnamoylthiazoles and Their AttemptedCyclization.-A practical route for the synthesis of the title compounds (III) (8 examples) from alkylthioureas (I) and bromoketones (II) is described. The attempted cyclization of these compounds to thiazolopyridones fails. -(BINU, R.; DEEPA, S.; RAJASEKHARAN, K. N.; Synth.