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Dementia and Mild Cognitive Impairment (MCI) are significant health issues that are a rising cost to society. They are monitored with cognitive tests during clinical appointments that are limited by the healthcare system capacity and patient's ability/willingness to attend. Current cognitive tests use behavioural measures and not direct measures of underlying cellular change. This causes delay in This work could never have been possible without the inspiration, support and acceptance of the long hours of work from my family including

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