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The homotopy analysis method HAM is employed to obtain symbolic approximate solutions for nonlinear coupled equations with parameters derivative. These nonlinear coupled equations with parameters derivative contain many important mathematical physics equations and reaction diffusion equations. By choosing different values of the parameters in general formal numerical solutions, as a result, a very rapidly convergent series solution is obtained. The efficiency and accuracy of the method are verified by using two famous examples: coupled Burgers and mKdV equations. The obtained results show that the homotopy perturbation method is a special case of homotopy analysis method. μ n l if and only if h n ∈ C μ , n ∈ N.Definition 2.2. The Riemann-Liouville fractional integral operator J α of order α ≥ 0, of a function f ∈ C μ , μ ≥ −1, is defined as

The analytical solution of the foam drainage equation with time- and space-fractional derivatives was derived by means of the homotopy analysis method (HAM). The fractional derivatives are described in the Caputo sense. Some examples are given and comparisons are made; the comparisons show that the homotopy analysis method is very effective and convenient. By choosing different values of the parameters in general formal numerical solutions, as a result, a very rapidly convergent series solution is obtained.