Ventricular tachycardia in patients with phenochromocytoma is rare. We report a patient with a norepinephrine-secreting extra-adrenal pheochromocytoma who had exercise induced ventricular tachycardia. Prior to diagnosis, the patient was treated with a selective beta 1 blocker, atenolol, which resulted in suppression of the dysrhythmia and amelioration of the hypertension. This is the first reported case of selective beta blockade suppressing ventricular tachycardia in a patient with a pheochromocytoma. Electrocardiographic abnormalities described in patients with pheochromocytoma are reviewed.
Cowden's Disease or multiple hamartoma syndrome is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract and genitourinary system. A large percentage of these patients have goiters or other thyroid abnormalities. Physicians should consider the diagnosis of Cowden's disease in patients presenting with thyroid disease and skin lesions such as papules or skin tags and if present these subjects should be screened for other malignancies associated with this disease.
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