Rosai-Dorfman disease (RDD) is a rare lymph proliferative disorder with nodal and extranodal involvements. We are presenting this case of Rosai dorfman disease with presentation in pinna of ear and with previous history of Rosai dorfman disease at multiple sites including lymph node. Cytological and histological examination of the submandibular lymph nodes and skin biopsy demonstrated evidences of RDD.
Aim:
The aim is to study the correlation of high myopia with macular thickness by optical coherence tomography (OCT).
Design:
Case control study.
Subjects and Methods:
Sixty patients visiting outpatient department, Department of Ophthalmology of a tertiary care hospital, were enrolled in the study. The macular thickness of 30 high myopes and 30 emmetropes was measured using OCT. All high myopes had a spherical equivalent of ≥-6.0 Diopters (D) and intraocular pressure <21 mmHg. All the participants were chosen after excluding other ophthalmic diseases or any history of ocular or refractive surgery.
Statistical Analysis:
Variables are expressed as mean ± standard deviation. Data analysis was performed using SPSS version 20. Unpaired and Paired t-test were used. P ≤ 0.05 was considered statistically significant.
Results:
The para and perifoveal retinal thickness were significantly thin in high myopic eyes as compared to emmetropic eyes. The central foveal thickness was 298.93 ± 38.813 μm in high myopes and 224.63 ± 16.439 μm in emmetropes, which was statistically significant P < 0.001.
Conclusion:
The macular thickness was significantly decreased in myopic eyes compared to emmetropic eyes. However, the central foveal thickness was significantly high in high myopes. Therefore, the analysis of macular thickness in the evaluation of macular diseases or glaucoma should be considered based on refractive errors and the location of measurement.
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