The paper describes topological modeling of antimycobacterial activity of 3-formyl rifamycin SV derivatives using a large series of molecular vis-à-vis topological descriptors. For the set of 53 derivatives of 3-formyl rifamycin SV no one variable model is possible, however, in multiparametric regression excellent model is obtained for modeling the activity. The results are discussed using variety of statistical parameters.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.