not easy to explain, there is experimental data suggesting that testosterone can influence neuromuscular transmission in the diaphragm of rats [2, 3]. Furthermore, it was seen after shorter rather than longer periods of treatment (2.5 weeks vs. 10 weeks) [4].We wished to highlight the problem of handling an increased catabolic state (of different origins) -or even a risk of it -in patients with primary or secondary male hypogonadism. This situation is often unnoticed and its influence on the body sometimes underestimated. In our opinion, the concentration of testosterone in serum should be restored in all hypogonadal patients in possible catabolic states. It is especially valid for males who have received high doses of anabolic-androgenic steroids for a long time. We believe that before major surgical procedures, the testosterone level should be maintained above the normal range. We also wonder whether such management should be considered before surgical procedures in males with andropausal hypogonadism (with low levels of total and free testosterone).