We investigate the relation between two types of space curves, the Mannheim curves and constant-pitch curves and primarily explicate a method of deriving Mannheim curves and constant-pitch curves from each other by means of a suitable deformation of a space curve. We define a “radius” function and a “pitch” function for any arbitrary regular space curve and use these to characterize the two classes of curves. A few non-trivial examples of both Mannheim and constant pitch curves are discussed. The geometric nature of Mannheim curves is established by using the notion of osculating helices. The Frenet–Serret motion of a rigid body in theoretical kinematics is studied for the special case of a Mannheim curve and the axodes in this case are deduced. In particular, we show that the fixed axode is developable if and only if the motion trajectory is a Mannheim curve.