Glaucoma is considered as a chronic progressive and usually symptomatic disease that destroys retinal cells and is one of the leading cause of preventable blindness worldwide, including India according to World Health Organization (WHO) studies. Although dawn of newer topical agents have modernized the management of glaucoma, the cost of these drugs pose a major hindrance to successful treatment since it limits entrée and amenability. AIMS AND OBJECTIVES:To analyze current prescribing trends in anti-glaucoma drugs, to perform a drug utilization study using WHO parameters, to identify drugs per prescription, category wise identification of drugs prescribed. MATERIALS AND METHODS: The present study was a retrospective cross sectional, observational record based study carried out at NKPSIMS & RC, Nagpur, India. RESULTS: Out of total 405 records assessed, 275 were males (68%) and 130 were females (32%). Average number of drugs per prescription was 1.8 while the average cost of therapy per prescription came out to be 54.4 Rs.Amongst them most commonly used drug was timolol which was used in 80 patients followed by pilocarpine (68 patients) and brimonidine (35 patients). In males timolol was most commonly prescribed while in females timolol, pilocarpine and betaxolol shared a dominated use. Least prescribed drugs were topical atropine (2 patients), both overall and in males, while dexamethasone was used least in females (1 patient).CONCLUSION: Awareness regarding use of generics on a large scale should be done, keeping in mind only sole purpose-to increase the benefit of the patient, decrease cost of the treatment and decrease side effects without affecting efficacy.
Aims and Objectives: The main objectives of the study were to describe the drug utilization pattern of anti-epileptic drugs (AEDs), to get an insight into the type and etiology of various forms of epileptic seizures, to review drug use and/or prescribing patterns, to study the effects (beneficial and adverse) of antiepileptic drugs. Materials and Methods: The present study was a prospective, non-randomized controlled single blinded trial, done at NKPSIMS and RC, Nagpur, India. Results: Out of 146 participants, 76 were male and 70 were females. Monotherapy was given in 102 patients (69.8%) while polytherapy was given in 44 patients (30.1%). Amongst the monotherapy, phenytoin was most commonly prescribed in 25 patients (17.1%) while levetiracetam and vigabatrin were least prescribed (1.3 and 2.7 respectively). Amongst the fixed dose combinations (FDCs) phenytoin + phenobarbital was most commonly prescribed. Conclusion: The findings of the present study should be generalized by performing such regular studies elsewhere in other parts of the country, so as to help in meticulous planning in order to reduce the expenditures in health care without affecting efficacy.
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