Enzymes of the glycolytic pathway as well as some ancillary enzymes were studied in normal red cells parasitized with Plasmodium falciparum in culture at varying parasitemias as well as in isolated parasites. The levels of all enzymes except diphosphoglycerate mutase, glucose-6- phosphate dehydrogenase, and adenylate kinase were elevated. Extreme elevations of hexokinase, aldolase, enolase, pyruvate kinase, and adenosine deaminase concentrations were noted. In most cases, electrophoretically distinct bands of enzyme activity were also seen. These findings partly explain the previously noted 50- to 100-fold increase in glucose consumption of infected red cells and suggest that further knowledge of these parasite enzymes and their genetic basis may aid both in designing new chemotherapy and in understanding the evolution of these parasites.
This study focuses on pre-service teachers' perspectives regarding how the process of completing the Performance Assessment for California Teachers (PACT) affected them academically, professionally, and personally. Pre-service teachers' perspectives were acquired using a survey instrument comprised of open-ended questions. In addition, pre-service teachers' selfconfidence levels pertaining to assessment task components of PACT (i.e., planning, instruction, Education Policy Analysis Archives Vol. 21 No. 56 SPECIAL ISSUE 2 assessment, reflection, and academic language) were measured prior to the execution of PACT portfolio assessment and these levels were compared to the actual scores on PACT. This study concludes with implications for teacher educators and teacher education programs implementing pre-service teacher assessments; these implications include policy level suggestions as well as a discussion of intended and unintended consequences of the PACT assessment on the pre-service teachers. Keywords: pre-service teacher assessments; teacher beliefs; certification/licensure; teacher education; PACT.
La evaluación de los docentes en formación inicial antes de la certificación: Perspectivas sobre la Evaluación del Desempeño de Maestros de CaliforniaResumen: Este estudio se centra en las perspectivas de docentes en formación acerca de cómo el proceso de completar la Evaluación de Desempeño de Maestros de California (PACT por sus siglas en inglés) los afectó académicamente, profesionalmente y personalmente. Perspectivas de los docentes en formación fueron adquiridas utilizando una encuesta con preguntas abiertas. Además, se midieron los niveles de auto-confianza relativos a componentes de la tarea de evaluación de PACT (es decir, la planificación, la enseñanza, la evaluación, la reflexión y el lenguaje académico) antes de la ejecución de la evaluación PACT y estos niveles se compararon con los resultados reales de PACT. Este estudio concluye con sugerencias para formadores de docentes y programas de formación de docentes que utilizan evaluaciones de docentes en formación. Se incluyen sugerencias a nivel de políticas, así como un análisis de las consecuencias intencionales y no intencionales de la evaluación de impacto en los futuros docentes. Palabras clave: evaluación de la formación docente; creencias docentes; certificación / licenciaturas; formación del profesorado; PACT.A avaliação dos professores em formação inicial antes da certificação: Perspectivas sobre a Avaliação de Desempenho de Professores da Califórnia Resumo: O presente estudo centra-se nas perspectivas de futuros docentes sobre como o processo de conclusão da Avaliação de Desempenho para Professores da Califórnia (PACT por sua sigla em Inglês) os afetou academicamente, profissionalmente e pessoalmente. Perspectivas de professores em formação foram adquiridos utilizando uma pesquisa com perguntas abertas. Além disso, foram medidos os níveis de auto-confiança em relação ao componente tarefa de avaliação PACT (isto é, planejamento, ensin...
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