12) Main, P.; Hull, S. E.; Lessinger, L.; Germain, G.; Declerq, P. J.; Woolfson, M. M.; *MULTAN: AA stereospecific synthesis of the basic crassin acetate nucleus, erythro-l-(hydroxymethyl)-14-hydroxy-4,8,12-trimethylcyclotetradeca-(E,E,E)-3,7,11-triene, has been achieved. Stereospecific syntheses of the two precursors to this ring system, (E,E)-3,7-dimethyl-9-(phenylthio)nona-3,7-dienal and (E)-2,8-bis(trimethylsiloxy)-2,7-dimethyloct-6-en-3-one, have been developed. These moieties were combined via an aldol condensation to yield erythro-9-hydroxy-l0-[ l-oxo-2-methyl-2-(trimethylsiloxy)propyl]-l-(phenylthio)-14-(trimethylsiloxy)-3,7,13-trimethyltetradeca-(E,E,E)-2,6,12-triene which, in a series of reactions, was cyclized to the titled 14-membered ring system.(2) Dauben, W. G.; Thiessen, W. E.; Resnick, P. R.

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