OBJECTIVE: To determine the impact of Human Deficiency Virus (HIV)/AcquiredImmunodeficiency Syndrome (AIDS) on the quality of life (QOL) on such patients in North India. DESIGN: A cross sectional study. SETTING: Outpatient setting and wards, Department of Medicine at a premier tertiary health care center, North India. PARTICIPANTS: Sixty-eight consecutive HIV/AIDS patients attending Medicine out patient department and/or admitted to the wards of All India Institute of Medical Sciences were administered a structured questionnaire by the HIV nurse coordinator. QOL was evaluated using the WHOQOL-Bref (Hindi) instrument. ANALYSIS: One way Analysis of Variance (ANOVA) was performed to find out significant difference between the clinical categories and socio-demographic variables on QOL domains. RESULTS: The overall QOL mean score on a scale of 0-100 was found to be 25.8. Similarly, on the scale of 0-100 the mean scores in the four domains of QOL in descending order were social (80.9); psychological (27.5); physical (17.7) and environmental domain (11.65). There was a significant difference of quality of life in the physical domain between asymptomatic patients (14.6) and patients with AIDS (10.43) defining illnesses (p<0.001) and asymptomatic and early symptomatic (12) patients (p=0.014). QOL in the psychological domain was significantly poorer in early symptomatic (12.1) (p<0.05) and AIDS patients (12.4) (p<0.006) as compared to asymptomatic individuals (14.2). A significant difference in QOL scores in the psychological domain was observed with respect to the educational status (p<0.037) and income of patients (p<0.048). Significantly better QOL scores in the physical (p<0.040) and environmental domain (p<0.017) were present with respect to the occupation of the patients. Patients with family support had better QOL scores in environmental domain. CONCLUSIONS: In our study, QOL is associated with education, income, occupation, family support and clinical categories of the patients.

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Coronary Artery Diseases (CAD) is a class of diseases that involve the heart or blood vessels. CAD mainly involves underlying mechanism of atherosclerosis which may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, dyslipidaemia, poor diet and excessive alcohol consumption. In India, more than 10.5 million deaths occur annually due to CAD. According to 2010-2013 RGI data, proportionate mortality from CVD increased to 23% of the total. Ayurveda vividly describes heart diseases in the context of Hridroga in different classical texts. These concepts can be applied to CAD also. It can be interpreted as Sannipataja Hridroga with Kapha-Vata predominance and it occurs due to Praana-Rasavaha srotodushti. A 50 year old male patient; already diagnosed as CAD since 2 years came to our OPD with complaints of Dyspnoea on exertion (DOE), chest heaviness and occasional pain with general weakness of the body since 1 week, with ECG, ECHO, TMT and Coronary Angiography reports which shows CAD changes. On investigation, slight increase in Serum Total Cholesterol and LDL were noted. The patient was advised to take 32 ml of Lasunairandadi Kashaya (decoction) with Hingu (150 mg) as Prakshepa Dravya (adjuvant) for 90 days along with the treatment as usual (TAU). Lasunairandadi Kashaya is mentioned in Sahasrayogam, Vridhi Prakaranam. Most of the drugs are Hridya (cardiac protector), Tridoshahara (alleviation of aggravated bodily humours), Ushna Veerya (hot in potency) and Katu Vipaka (state of food/drug after digestion) and Lasuna (garlic) is Prabhanjananam Sreshtam (best for correcting Vata Dosha), which in turn helps in Srotosodhana (purifies the vessels) and Vataanulomana (downward movement of Vata). At the end of the study there was significant reduction in the TMT score along with the symptoms.

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