A water sampling survey on the Hualapai Indian Reservation delineated two areas as targets for possible clusters of mineralized breccia pipes. Samples were collected from all known flowing wells and springs on the Reservation-totalling 75. Statistical analyses, including mean, standard deviation, correlation coefficients, scatter plots, and R-mode factor analyses, were determined on the samples using 47 elements and other chemical parameters. Silver, Hg, Mo, and Pb, elements associated with uranium in breccia pipes, appear to be effective pathfinders for hydrogeochemical surveys for uranium-rich breccia pipes. Eight springs were found to be anomalous, and their recharge areas should be thoroughly searched for mineralized breccia pipes: Travertine Falls Spring, Lost Travertine Falls Spring, two seeps at the mouth of Separation Canyon, Beecher Spring (south of the Ridenour Mine), Horsehair Spring, Mohawk Spring, Warm Springs, and Pumpkin Spring. Of these eight anomalous springs, the two providing the best targets for exploration are Mohawk Spring and Beecher Spring. As a result of the hydrogeochemical survey in 1982, both areas were searched in detail for mineralized breccia pipes with considerable success. Several mineralized breccia pipes have been located near Beecher Spring; likewise several pipes have been found in the vicinity of Mohawk Spring, including one (the Mohawk Canyon pipe) that was drilled in 1984 and determined to contain anomalous concentrations of U (ore grade), Cu, Zn, Pb, As, Ag, Co, Ni, and Mo. Of the 75 sites, many are magnesium, calcium, bicarbonate waters which are within safe drinking standards for the inorganic chemical parameters tested in this report-these waters remain to be tested for organic compounds. Several spring sites located in the bottoms of canyons (such as Horsehair and Pumpkin) are sulfate and chloride waters, most of which are not potable. The aquifer providing water for the most sites sampled in this study was the Cambrian Muav Limestone. The next most common aquifers were the Tertiary and Quaternary gravels and conglomerates, particularly the Frazier Well gravel, and the Coconino Sandstone. It is also worth noting that one of the 5 springs (Upper Diamond Spring) with the greatest discharge on the Hualapai Reservation emanates from the Redwall Limestone.