The aim of this study was to investigate and compare Mirabilis jalab L. extracts obtained in ultrasonic condition with different water/methanol and water/ethanol extraction mixture acidified with 0.1% HCl. The extracts were analyzed for monomeric anthocyanins contents and antioxidant activities. The highest anthocyanins content (3197.8 mg/L) and best antioxidant activity were obtained for Mirabilis jalab extract with 100% ethanol. Also, there is a good correlations between antioxidant activity (R 2 = 0.9332 and 0.9712) for water/ethanol and methanol series extracts respectively.