SummaryA 50-year-old known patient with ulcerative colitis with relapses and remissions presented with clinical features suggestive of bowel obstruction. Radiological studies confirmed an obstructive mass lesion in the hepatic flexure of the colon. Due to bowel obstruction and suspicion of malignancy an emergency laporatomy and partial ileo-colectomy was performed. A complex polypoid mass comprising numerous slender straight finger-like villi lined by non-neoplastic colonic mucosa with serrations at the base and prominent lamina proprial smooth muscle splaying was identified and a diagnosis of filiform polyposis was made. We report this unusual manifestation of an inflammatory reaction presenting as a colonic mass clinically and radiologically mimicking malignancy.
Marked plasmacytosis in the bone marrow is a rare finding in young people. If present it is secondary to an underlying disease condition. Castleman disease is a rare form of lymphoproliferative disorder. Due to its rarity, it is not frequently considered in the differential diagnosis of lymphadenopathy. As in any other lymphoproliferative disorder Castleman disease can also be associated with various immune mediated cytopenia. This case report is on a teenager with persistent lymphadenopathy of whom the presence of marked bone marrow plasmacytosis led to the diagnosis of plasma cell type Castleman disease which went into complete remission with single agent vincristine and radiotherapy with subsequent severe immune thrombocytopenia during follow up.
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