Background: Nasal Polyp is commonly encountered in clinical practice and important from clinical and pathological perspectives as they have varieties of histological patterns. The Polypoidal masses in nasal cavity form a complex group of lesions with wide spectrum of histopathological features, mainly grouped under allergic and inflammatory. Histopathological examination shows a spectrum of lesions ranging from the non-neoplastic ones to neoplastic tumors.Methods: Present study included 153 polypoidal lesions of the nasal cavity during a period of one year. All the tissues were fixed in 10% buffered formalin, processed, stained with H & E and studied for various histopathological patterns. Periodic acid Schiff's and reticulin stains were used wherever necessary.Results: classifying the sinonasal lesions according to histo-pathological features into various types helps us to know the clinical presentation, treatment, clinical outcome and prognosis of the disease. Although most of nasal polyps sent for histopathology are inflammatory, secondary to infection or allergy, various benign and malignant lesions of nose may present as polypoidal masses, Conclusion:The study recommends, all polyps need histo-pathological examination.

Guillain-Barre syndrome (GBS) is a complicated degenerative neurological disorder which can be acute or chronic in nature. It is an acquired condition which is characterized by progressive, symmetrical, proximal and distal tingling and weakness. Muscle stretch reflexes are decreased to absent and loss of sensation is common. Etiology remains unclear but pathophysiology includes demyelination of spinal nerve roots. Death is rare. Early diagnosis and prompt referral should occur in severe cases due to the incidence of potential ventilation   failure and cardiovascular instability in some patients. The case of a 26-year-old male presenting to a physician is described. The importance of a correct diagnosis by the physician and the subsequent management is reviewed. Key words: Guillain-Barre syndrome, extremity weakness, peripheral nerves, trauma