Introduction: The metabolic syndrome (MS) encompasses many metabolic abnormalities and the insulin resistance is considered as one of the most significant denominators. The chronic kidney disease (CKD) is an emerging health problem but only few patients would reach the end stage renal disease. There exists an increasing strong association between MS and CKD, but up until now the link between MS and CKD is unclear and there are few studies regarding the renal histology in MS. Methods: We describe an acute tubulointerstitial nephritis case, due to both infective and pharmacological aetiology, overlapping relevant histological changes (focal segmental glomerulosclerosis [FSG], hyaline arteriosclerosis) in a patient with MS and previously normal renal function. Despite the severe vascular finding (elevated renal arterial resistive index), the patient recovered a normal renal function. Results: We reviewed the kidney pathological studies in MS and analyzed the principal renal histological images of glomerulomegaly, segmental glomerulosclerosis, and obesity-related glomerulopathy. Conclusion: Despite the strong association, the renal involvement in MS has not been proven. A greater knowledge of the combination of histological renal changes in MS can help to understand the pathophysiological mechanism(s) of MS.

A NUMBER of complex compounds of transition metals are known which contain clusters of metal atoms1 (three, four, or six) directly bonded together, with ligands at the periphery of the cluster. We report two new complexes of this type, which contain platinum(0).The first cluster compound, mono-triphenylphosphineplatinum(O), (A), was obtained by allowing tetrakis(triphenylphosphine)platinum(0)2 to react (in air) with either cyclo-octa-1,5-diene, or its 1,3-isomer. A number of products with coordinated olefin occur in each case, but a brown compound (A) may be isolated (ca. 50% yield) by virtue of its low solubility in ether. Entirely different (monomeric) products are obtained by performing the reactions in the absence of oxygen.

The chemistry of the zerovalent state in nickel, palladium, and platinum compounds is reviewed. After a historical introduction in which the development of this chemistry is analyzed in terms of the current theory of the stabilization of low valency states, the most interesting classes of zero valent compounds are described. The stability and properties of these compounds are discussed and related to the nature of the ligands and the coordinated metal. The catalytic properties of these zerovalent derivatives toward olefins, diolefins, and acetylenes are considered in connection with the facility of ligands exchange, the varia tion of coordination number, and the stereochemistry. A discussion of the π bond is reported.'he first coordination compound with a low oxidation number, tetracarbonylnickel (HI), was discovered in 1890. Despite extensive efforts, however, very few substances of this type were synthesized in the next 50 years.The lack of any knowledge on the structure and bonds of these com pounds was responsible for the poor results. In fact, when tetracarbonylnickel was first prepared, Werner's theory had not as yet been postulated, and even later the theory was not extended to the carbonyls because they were considered anomalous compounds, owing to their chemical and physical properties.The studies on coordination compounds with the central metal in a low oxidation state began to fluorish just prior to World War II. Nickel, palladium, and platinum were particularly investigated for the following reasons:318

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The compound with the composition [Co(NH,),(NO,),] NO,,HNO,, originally described by S. M. Jorgensen, is reformulated cis-[Co(NH,),(HNO,) (NO,)] (NO,),, on the basis of spectroscopy. A new convenient method of preparation is described.