A study of cross-impact degree and morpho-functional correlation characteristics of primary open angle glaucoma and age-related macular degeneration was performed at 25 clinical sites in Russia and some CIS countries from January through May 2013. The study final protocol included 87 patients (108 eyes) divided into two groups, mean age of patients was 66.6 ± 5.65 years (min 55; max 81). Intragroup and intergroup variance analysis did not establish any significant difference in the macular area between the «glaucoma» group and the «glaucoma + AMD» group depending on the disease stage. The findings suggest that macular degeneration develops subsequent to a preexisting glaucomatous state.

The article provides data on general and primary glaucoma morbidity, the availability of modern diagnostic equipment in Federal districts of the Russian Federation. There is information from 82 regions of the country presented. The tables present the distribution of patients according to glaucoma stages. Indices are arranged into groups according to Federal districts

Objective: to determine the efficiency of the treatment for glaucoma and its accompanying costs in patients with II-III stages of open-angle glaucoma. Material and methods. The multicenter study which was conducted by 35 investigators in 29 clinical centers in 4 CIS countries from December 2013 to April 2014 took into account the results of the treatment of 115 patients (187 eyes) with glaucoma. The cost and «cost-effectiveness» of the intraocular pressure (IOP)-lowering treatment were calculated with the account of IOP-level compensation. Results. The average cost-effectiveness was 13.94 ± 0.66 rubles/day, which was comparable to the theoretical cost of the treatment but 32 % exceeded the price that patients actually paid for the treatment. As for the monotherapy with prostaglandin preparations and the fixed combination of beta-adrenoblocker and prostaglandin analogue (BB + PG), the difference between the actual price and cost-effectiveness was 44 %. At the same time, this difference in the application of the fixed combination of beta-adrenoblocker and carbonic anhydrase inhibitor (BB + CAI) made up 64 %. Conclusion. It is cheaper to achieve a controlled IOP level in the application of the fixed combination BB + PG compared to the BB + CAI fixed combination treatment.

Objective: to study the intraocular pressure (IOP) in patients with primary open-angle glaucoma during the treatment with hypotensive drugs depending on age, medical history, stage of disease and the central thickness of the cornea. Material and methods. 812 right eyes of 812 patients were examined, 637 of 812 were glaucoma patients and 175 healthy people of the control group. Results. The level of the intraocular pressure was significantly higher in patients with severe glaucoma than in patients with moderate glaucoma or healthy people. There was no significant difference in the central corneal thickness between glaucoma patients and healthy people (both male and female). The IOP level was higher in the group of patients treated with non-fixed combination of beta-blockers and prostaglandins regardless of the disease stage. The IOP compensation was found in 69.9 % of patients with moderate glaucoma and 14.4 % of patients with severe glaucoma. Conclusion. The results of the study can be used as clinical guidelines for determination of the optimal IOP range while choosing the optimal IOP-lowering medications at the start of therapy and during the follow-up of patients with moderate and severe glaucoma.