Tuberculosis of the thyroid gland occurs only rarely. Since extrapulmonary tuberculosis is now seen relatively more frequently the existence of this condition should be recognized. The cases of two patients with tuberculosis involving the thyroid are presented. The first, an Asian immigrant, presented with a painless goitre with no evidence of tuberculosis elsewhere. The second was an English woman who presented with hypothyroidism due to destruction of the thyroid by tuberculosis, and who subsequently died with disseminated tuberculosis; this is the only case to report the association between myxoedema and tuberculous thyroiditis. Other manifestations of thyroid tuberculosis and the pathological types are discussed.

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Δ1 ‐trans‐tetrahydrocannabinol (Δ1‐THC; 10 mg) or a placebo was given orally on 7 days to two groups of six patients on a cross‐over pattern with 7 days rest between. The patients were hospitalized, suffering from inoperable bronchogenic carcinoma, subjected to radiation therapy, and anxious. Self‐rating mood scales were filled in before, and 2 and 6 h after ingestion on the first and seventh day of medication. Records of sleep, pain, general well‐being, temperature, cardiovascular and gastrointestinal parameters were kept. Δ1‐THC caused drowsiness and improved night sleep, reduced pain, increased fatigue and confusion and reduced elation and vigour; it caused slight tachycardia and hypotension as also did placebo. The effects of Δ1‐THC were stronger after 2 h than 6 h and no tolerance had developed at 7 days. The management of stressful patients was considered to have been improved by the drug.

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