Panel peer review is widely used to decide which research proposals receive funding. Through this exploratory observational study at two large biomedical and health research funders in the Netherlands, we gain insight into how scientific quality and societal relevance are discussed in panel meetings. We explore, in ten review panel meetings of biomedical and health funding programmes, how panel composition and formal assessment criteria affect the arguments used. We observe that more scientific arguments are used than arguments related to societal relevance and expected impact. Also, more diverse panels result in a wider range of arguments, largely for the benefit of arguments related to societal relevance and impact. We discuss how funders can contribute to the quality of peer review by creating a shared conceptual framework that better defines research quality and societal relevance. We also contribute to a further understanding of the role of diverse peer review panels.

Aim Cardiac diseases remain a leading cause of cardiovascular disease (CVD) related hospitalisation and mortality. That is why research to improve our understanding of pathophysiological processes underlying cardiac diseases is of great importance. There is a strong need for healthy and diseased human cardiac tissue and related clinical data to accomplish this, since currently used animal and in vitro disease models do not fully grasp the pathophysiological processes observed in humans. This design paper describes the initiative of the Netherlands Heart Tissue Bank (NHTB) that aims to boost CVD-related research by providing an open-access biobank. Methods The NHTB, founded in June 2020, is a non-profit biobank that collects and stores biomaterial (including but not limited to myocardial tissue and blood samples) and clinical data of individuals with and without previously known cardiac diseases. All individuals aged ≥ 18 years living in the Netherlands are eligible for inclusion as a potential future donor. The stored samples and clinical data will be available upon request for cardiovascular researchers. Conclusion To improve the availability of cardiac tissue for cardiovascular research, the NHTB will include extensive (cardiac) biosamples, medical images, and clinical data of donors with and without a previously known cardiac disease. As such, the NHTB will function as a translational bridge to boost a wide range of cardiac disease-related fundamental and translational studies.