Purpose of the study. The study of the diagnosis and treatment of destructive forms of acute pancreatitis and the identification of possible ways to optimize them. Materials and methods. Destructive forms of acute pancreatitis were found in 16,8%. The algorithm for treating acute destructive pancreatitis consisted in artificial ventilation of the lungs, adequate infusion therapy, peridural anesthesia, setting up a nasoenteric probe, stimulating the bowels, correcting hemodynamics, intra- and extracorporal detoxification, antisecretory, anti-bacterial, hepatoprotective, cerebroprotective, antioxidant therapy, directed immune correction, use of anti-enzyme drugs, suppression of the release of mediators inflammation, external secretory activity of the pancreas. Medical video laparoscopy and puncture interventions under the control of ultrasound were used as the first stage of surgical treatment. The indications for traditional surgical interventions are large areas of aseptic destruction, unlimited infected pancreatic necrosis, infection of necrotic areas with complete cell sequestration, abscesses with large sequesters, abdominal phlegmon, signs of progressive multiple organ failure and the development of arousal hemorrhage, perforation of cystic formations in the abdominal cavity, perforation of a hollow organ, purulent peritonitis. Results. The developed therapeutic tactics allowed, in destructive forms of acute pancreatitis, to achieve a reduction in overall mortality to 23,4%. Conclusion. Diagnostic and treatment tactics for destructive forms of acute pancreatitis should be standardized depending on the timing, severity of the disease, localization and prevalence of the destructive process, systemic and local complications. Keywords: acute, destructive, pancreatitis, diagnosis, treatment.
Summary: Introduction. Diverticular disease of the large intestine accounts for 30-60 % of all organ pathologies, among which acute diverticulitis is 20-60 %. The aim of the study was to select therapeutic and diagnostic measures for acute diverticulitis of the large intestine with the development of local inflammatory complications. Materials and methods. The results of treatment of 68 patients with acute diverticulitis were analyzed. Diagnostics included clinical and laboratory studies, irrigography, colonoscopy, ultrasound, computed tomography. Research results. 61.8 % of patients with Ia, Ib stages of acute diverticulitis were treated conservatively. Drainage was installed under ultrasound control into the abscess area in 10.3 % of patients with acute diverticulitis in stage Ib. Laparoscopic intervention was performed in 22.1 % of patients. Operated on emergency indications 33.8 % of patients with II, III, IV stages of acute diverticulitis from laparotomic access. Postoperative mortality was 8.7 % of cases. Conclusions:1. Comprehensive assessment of clinical, radiological, endoscopic data, ultrasound, CT data allows to establish the clinical form and stage of acute colon diverticulitis and to choose the correct treatment tactics. 2. Multicomponent drug therapy is a rational method of treatment in patients with stage Ia, Ib acute diverticulitis. 3. Surgical treatment is indicated in acute diverticulitis complicated by perforation and peritonitis, profuse intestinal bleeding or intestinal obstruction caused by cicatricial stricture. 4. The proposed therapeutic and diagnostic algorithm for acute diverticulitis of the large intestine with the development of pyoinflammatory complications should be introduced into the practice of general surgical departments.
Summary. The problem of hemorrhagic complications of destructive pancreatitis is relevant. The aim of the study was to study the frequency and sources of hemorrhagic complications in patients with pancreatic necrosis, to evaluate the tactics of diagnosis and the effectiveness of methods to stop bleeding. Materials and methods. A study of the results of treatment of 40 patients with acute necrotizing pancreatitis was conducted. Results and its discussion. In 67.5 % of patients with acute necrotizing pancreatitis, hemorrhagic complications in the form of arrosive bleeding were observed. A method of endovascular occlusion of vessels using Gianturco spirals or stent grafts to stop arrosive bleeding in acute necrotizing pancreatitis has been introduced in the clinic. In 37.0 % of cases, repeated signs of arrosive bleeding were observed. In acute necrotizing pancreatitis complicated by arrosive bleeding, mortality was 44.4 %. Conclusions. The main cause of hemorrhagic complications in acute necrotic pancreatitis is acute necrotic changes, during infection of which arrosia of adjacent vessels occurs. The predominant tactic in case of bleeding from the retroperitoneal space against the background of minimally invasive treatment is clamping of drains, endovascular hemostasis using Gianturco spirals or stent grafts and the use of hemostatic soluble gauze (hemostop). Mortality in the development of arrosive bleeding in acute necrotic pancreatitis is 44.4 %.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.