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Background and AimUnder normal circumstances, a urine albumin excretion of 5-10 mg/L is considered to be normal. Micro-albuminuria is, however, defined as a level of albumin in the urine that is between 20 mcg/min, and 200 mcg/min (30-300mg/24h) with normal urine flow of 1 ml/min.The aim of this study is to assess the prevalence of micro-albuminuria and associated factors among adult type two diabetes mellitus clients in public hospitals of Jigjiga town, Somali region, Ethiopia, from April 1 to July15, 2020Methods: Institutional based cross-sectional study design was used from April 1 to July 15, 2020. A pre-tested structured questionnaire was used to collect a data from 204 Type 2 diabetes mellitus patients visiting at Karamara general and Jigjiga University referral hospitals for follow up. Descriptive statistics was computed. Logistic regression model was used to identify covariates using SPSS version 20. The direction and strength of statistical association was measured by odds ratio with 95 % CI and a P-value < 0.05 was considered as statistically significant.Results: The prevalence of micro-albuminuria was 48.0% with [95% CI (41.2, 54.9)] Duration of DM between 11-20 years [AOR=3.71; 95% CI (1.45, 9.49)] Family history of hypertension [AOR=2.24; 95% CI: (1.02, 4.70)] Systolic blood pressure [AOR=3.36; 95% CI:(1.39, 8.13)], Low density lipoprotein [AOR=5.60; 95%CI: (2.22,14.11)] High density lipoprotein [AOR=5.210;95%CI:(2.067,13.131)] and Glycated hemoglobin [AOR = 3.246; 95% CI (1.356, 7.78)] were significantly associated with micro-albuminuriaConclusion: There is a significant level of micro-albuminuria among type 2 diabetes mellitus patients. Effective secondary prevention program directed on blood glucose and lipid with steps to improve blood pressure are critical in undertaking in the setting and regular screening of micro-albuminuria is needed so that an early preventive and treatment measures against its burden are put in place.

Background: Hypertension is a common, non-communicable disorder of public health significance. Abnormalities in haemostasis and blood rheology have been linked to target organ damage (TOD) in hypertension. Microalbuminuria (MA) is an independent predictor of TOD. Methods: A cross-sectional study was carried out among 107 consecutively recruited hypertensives attending the Cardiology Clinic at ABUTH, Zaria, Nigeria. Complete blood counts, haemostatic screening tests and microalbuminuria assay were performed on blood and urine specimens. Results: The mean age of participants was 50.2±11.3 years and 59.3±18.2 years for females and males respectively with a female predominance (91/107; 85%). The frequencies of abnormal platelet counts, prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen, D-dimer and MA were 15%, 57%, 54.2%, 64.5%, 100%, 25.2%, and 41% respectively. Participants with poor BP control had an increased risk of derangements in aPTT and platelet counts (OR = 1.4, 1.4) but there was no significant difference in means with BP for aPTT, fibrinogen, and platelets (p = 0.517, 0.257 and 0.525 respectively). The impact of the duration of hypertension was shown in D-dimer levels up to 10 years. Participants on ARB/ACEI- containing regimens showed a higher risk of derangement in TT, aPTT, PT and D-dimer in contrast to platelet counts (OR = 0.96, p = 0.836). Haemostatic parameters showed weakly positive, statistically significant correlation on regression analysis. Conclusion: There is a high prevalence of, and positive correlation between haemostatic abnormalities and MA among hypertensives in Northern Nigeria. Abnormal haemostatic screening tests may indicate MA and increased risk of TOD.