Three bench-scale resorption systems were compared with respect to the degree of conversion, the specific cooling power, and the influence of the working condition on the temperature equilibrium drop. The mass of refrigerant that reacted during specified periods of each working condition studied was assessed gravimetrically. The three systems had MnCl2 in the main reactor, and they were designed to provide a cooling effect at 0 and at −5 °C. However, each system had a different salt (BaCl2, NaBr, or NH4Cl) in the reactor employed for cold production. The system with NH4Cl was the most suitable for cold production at the temperatures indicated above, whereas the system with BaCl2 was not suitable to operate at these levels of cooling production. Thus, we designed and manufactured a larger resorption system and assessed the feasibility of using this system to refrigerate a 33 L cold box, with two temperature zones. When the ambient temperature was 30 °C, the air temperature in the bottom of the cold box could be kept below 0 °C for 5 h, while the temperature of the upper zone remained below 6 °C for about 2.5 h.