Lately human have become more apprehensive for the health and their food relationship. Egg considered cheap source of animal protein. Eggs are rich in various essential nutrients that contribute to the quality of human diet. But its cholesterol can contributes with some human serious disease. The current study examines the hypothesis that assumed addition of antioxidant such as CAX, SS, B or their mixtures to the diet can produce functional egg from Fayoumi hens at late phase of egg production. A number of 168 Fayoumi hens (46weeks of age) were randomly assigned into 8 dietary groups as follows: Basal diet alone or with CAX (6 ppm), SS (0.5 g/kg), B (1 g/kg), CAX+SS, CAX+B, SS+B, and CAX+SS+B separately. Forty eight eggs (6 per each group) were analyzed for estimating cholesterol and total antioxidant capacity. Egg of hens fed a combination of CAX+SS+B which had the best total antioxidant capacity value, while the CAX group recorded the best lowest cholesterol value compared to other groups (P < 0.05). It could be concluded that basal diet supplemented with CAX, SS, B alone or with mixture of them may have lowering effect on yolk total cholesterol. This could lead to produce functional eggs which have positive effects on human health and favorable for those suffering from heart syndromes.