Structured Abstract Background COVID-related misinformation is prevalent online, including on social media. The purpose of this study was to explore factors associated with user engagement with COVID-related misinformation on the social media platform, TikTok. Methods A sample of TikTok videos associated with the hashtag #coronavirus were downloaded on September 20, 2020. Misinformation was evaluated on a scale (low, medium, high) using a codebook developed by experts in infectious diseases. Multivariable modeling was used to evaluate factors associated with number of views and presence of user comments indicating intention to change behavior. Results 166 TikTok videos were identified and reviewed. Moderate misinformation was present in 36 (22%) videos viewed a median of 6.8 million times (interquartile range, 3.6—16 million), and high-level misinformation was present in 11 (7%) videos viewed a median of 9.4 million times (interquartile range, 5.1—18 million). After controlling for characteristics and content, videos containing moderate misinformation were less likely to generate a user response indicating intended behavior change. By contrast, videos containing high-level misinformation were less likely to be viewed but demonstrated a non-significant trend towards higher engagement among viewers. Conclusions COVID-related misinformation is less frequently viewed on Tiktok but more likely to engage viewers. Public health authorities can combat misinformation on social media by posting informative content of their own. Lay Summary COVID-related misinformation is prevalent online, including on social media. The purpose of this study was to explore factors associated with user engagement with COVID-related misinformation on the social media platform, TikTok. We reviewed a sample of 166 TikTok videos associated with the hashtag #coronavirus posted between the beginning of the pandemic and September 2020. Misinformation was evaluated on a scale (low, medium, high) using a codebook developed by experts in infectious diseases. Moderate misinformation was present in 36 (22%) videos viewed a median of 6.8 million times, and high-level misinformation was present in 11 (7%) videos view a median of 9.4 million times. After controlling for characteristics and content, videos containing moderate misinformation were less likely to generate a user response indicating intended behavior change. By contrast, videos containing high-level misinformation were less likely to be viewed but demonstrated a trend towards higher engagement among viewers. Public health authorities can combat misinformation on social media by posting informative content of their own.

Background The true prevalence of low sexual desire among women is disputed among researchers due to the complex nature and presentation of women’s sexual problems. Aim To qualitatively analyze the aspects of libido/sexual desire frequently discussed by Reddit users and compare them with the current understanding of female sexual well-being and sexual desire disorders. Methods By using the Reddit application programming interface, the TwoXChromosomes subreddit was queried for posts with the keywords libido and sex drive. Posts that were deleted or unrelated to themes of libido/sex drive were excluded. A total of 85 threads—63 queried from the keyword libido and 22 from sex drive—and approximately 2900 comments were qualitatively analyzed per the grounded theory approach. Five independent researchers read and coded each thread to identify dominant themes and emergent concepts. Outcomes Outcomes of interest included codes related to sexual dysfunction, libido, orgasm, masturbation, types of sex, psychology, relationships, intimacy, treatment, medications, and health care. Results Posters were primarily heterosexual women in their 20s and 30s. The code categories with the highest frequency were relationships (22.7%, n = 272), libido (22.2%, n = 210), psychological (20.2%, n = 191), medications (7.29%, n = 69), and intimacy (6.0%, n = 57). Users frequently described a decrease in libido secondary to medications, particularly antidepressants and hormonal birth control. Many users discussed the challenges of navigating a relationship with low sexual desire and the resulting sexual distress. Posters described feelings of sadness, anxiety, and guilt due to their low desire. Additionally, users discussed the role that sex plays in relationships, whether as a way to develop intimacy between partners or to achieve orgasm. Finally, posters expressed dissatisfaction with health care addressing their concerns surrounding sexual desire. Clinical Implications The study findings—namely, the impact of medications on sexual health, the interaction of sexual desire and mental health, and cited examples of inadequate sexual health care—can help guide sexual well-being research, diagnosis, and public policy. Strengths and Limitations Using Reddit as a data source allowed for the analysis of women’s experiences outside the preestablished concepts of female sexual desire. Limitations to the study include the potential for posts to be deleted by moderator guidelines, the young demographic distribution of Reddit users, and the popularity-based structure of subreddit threads. Conclusion Our results emphasize the psychosocial aspects of sexual desire and the need to redefine sexual problems to encompass the complex nature of female sexual well-being.