Chondrosarcoma of a rib is a very rare malignant tumor of the bone. Most patients are present with an enlarging painful anterior chest wall tumor. We present a case of 32-years old female with a thoracoabdominal tumor size of 20 cm × 16cm involving the left 9th rib. Since chondrosarcoma is less sensitive to chemotherapy and radiotherapy, surgical treatment with extensive resection with a sufficient margin is considered first-line treatment. Sufficient soft-tissue reconstruction of the thoracic wall after extensive resection represents a formidable challenge. This article aims to illustrate the possibility of resection of the six last ribs with no complicated reconstruction technique.

We report a case of unexpected spontaneous regression of thymoma in a 44-year-old patient, referred with clinical, biological, and electrophysiological findings of Myasthenia gravis. The patient was stable on synthetic Acetylcholesterase inhibitors, immunosuppressants, and corticosteroids. A chest computed tomography (January 2020) revealed a well-defined tumor in the anterior mediastinum. Surgical removal was decided. Unfortunately, because of the covid 19 pandemic, the surgical activity of the department of thoracic surgery was suspended. The patient was discharged and re-admitted nine months later. A new chest computed tomography (September 2020) was performed, revealing a net regression of the anterior mediastinal tumor. The long axis of the tumor decreased from 97mm to 28mm. A Video-assisted thoracoscopic thymothymectomy was performed. The histopathological study of the specimen revealed a Thymoma B3, according to the world health organization (WHO) classification, without any necrosis, hemorrhagic or sclerotic cells. The spontaneous regression of thymic epithelial tumors is reported as rare. Surgical excision should be performed, even if tumor volume regression is observed. After surgical resection, the anatomopathological studies of the specimens could sometimes find some elements that explain the regression of these tumors. In our case, we suppose that the intake of corticosteroids by our patient could have played a role in this tumor regression.