Otorhinolaryngological infections are common pathologies especially in children, their clinical manifestations are varied. Knowledge of the microbial ecology of these infections in the ENT sphere may be important for the choice of probabilistic antibiotic therapy, but also for adapting and adjusting the treatment in therapeutic failure situations and complications. This is a descriptive retrospective study between January 2017 and August 2018. Including all samples taken in the ENT field in patients hospitalized in the ORL service of Med VI University Hospital of Marrakech. Of the 115 samples, bacterial confirmation was found in 87% of cases. The bacteriological profile was dominated by Gram-positive bacteria in 52% of cases. Isolated strains were mainly represented by Streptococcus (28%), followed by Staphylococcus aureus (22%). Enterobacteria accounted for 34% of isolates dominated by Klebsiella pneumoniae found in 20.5% of cases. The study of antibiotic susceptibility of isolated strains revealed a penicillin sensitivity of 98% in isolates of Streptococcus pneumoniae. A 75% sensitivity to amoxicillin was revealed in Enterococcus and all strains of Staphylococcus aureus were sensitive to meticillin. In enterobacteria, resistance to C3G was 18%, 38% to fluoroquinolones, 35% to cotrimoxazole and 29% of strains were resistant to Gentamycin. The multi-resistant strains of Pseudomonas aeruginosa were found in 8% of cases.

Vitamin D (Vitamine D), classically recognized as an important player in bone and phosphocalcic metabolism, has shown, through recent studies, its involvement in the pathogenesis of insulin resistance in case of deficiency. The aim of this work is to describe the profile of vitamin D in a type 2 diabetic population and to correlate the vitamin D status with the different metabolic parameters in this population admitted in the University Hospital of Marrakech. It is a descriptive crosssectional study of a population of type 2 diabetic patients, coming for a follow-up assessment of diabetes and having performed an evaluation of the level of 25 hydroxy vitamin D3 in blood. Demographic, clinical, evolutionary and biological data were collected. The mean of 25 (OH) vitamin D3 was 12.55 ± 8.14 ng / ml for the group, and was 13.15 ± 8.93 ng / ml for women and 11.82 ± 7.31 ng / ml for men. These patients were classified into three groups: Group 1: 25 (OH) D < 10 ng / ml objectified in 37 patients (44%); group 2: 25 (OH) D between 10 and < 29 ng / ml in 43 patients (51.2%) and group 3: 25 (OH) D > 30 ng / ml present in 4 patients in this population (4, 8%). Several studies have reported an association between vitamin D status and the development of type 2 diabetes. Experimental studies have suggested that vitamin D deficiency decreases insulin sensitivity, carbohydrate tolerance and β-pancreatic function. The data of this work underline the high frequency of vitamin D deficiency in the Moroccan population suffering from type 2 diabetes.