The aim of this study was to detect and describe the existence and incidence
of anatomical variations of the celiac trunk and superior mesenteric artery.
The study was conducted on 150 persons, who underwent abdominal Multi-
Detector Computer Tomography (MDCT) angiography, from April 2010 until
November 2012. CT images were obtained with a 64-row MDCT scanner in order to
analyze the vascular anatomy and anatomical variations of the celiac trunk
and superior mesenteric artery. In our study, we found that 78% of patients
have a classic anatomy of the celiac trunk and superior mesenteric artery.
The most frequent variation was the origin of the common hepatic artery from
the superior mesenteric artery (10%). The next variation, according to
frequency, was the origin of the left gastric artery direct from the
abdominal aorta (4%). The arc of Buhler as an anastomosis between the celiac
trunk and superior mesenteric artery, was detected in 3% of cases, as was the
presence of a common trunk of the celiac trunk and superior mesenteric artery
(in 3% of cases). Separate origin of the splenic artery and the common
hepatic artery was present in 2% of patients. The MDCT scanner gives us an
insight into normal anatomy and variations of the abdominal blood vessels,
which is very important in the planning of surgical interventions, especially
transplantation, as well as in the prevention of complications due to
ischemia.
This study aimed to evaluate principal morphological and morphometric characteristics of accessory canals (ACs) of the anterior maxilla, as well as to analyze the relationship with nasopalatine canal (NPC) type. The results of our study showed that ACs were observed in almost 50% of participants. They were mostly presented bilaterally and in a curved shape, with a palatal foramen position. The morphometric characteristics of ACs were significantly influenced by NPC type. NPC type had the strongest impact on the distance between the NPC and AC, as well as on the distance between the AC and the facial aspect of buccal bone wall, in inferior parts of the alveolar ridge. On the other hand, the distance between the AC and central incisors was not significantly influenced by NPC shape in the lower region of the anterior maxilla. However, the participants with the banana-type of the NPC expressed the reduction in distance from the AC to the central incisor at the upper part in comparison with the subjects with the cylindrical-type of the NPC. On the basis of the results of this study, the simultaneous estimation of ACs and the NPC seems reasonable, as this approach may be useful in the prevention of complications which could occur during implant surgery interventions.
In the past few years, intensive research has focused on corneal stem cells as an unlimited source for cell-based therapy in regenerative ophthalmology. Today, it is known that the cornea has at least two types of stem cells: limbal epithelial stem cells (LESCs) and corneal stromal stem cells (CSSCs). LESCs are used for regeneration of corneal surface, while CSSCs are used for regeneration of corneal stroma. Until now, various approaches and methods for isolation of LESCs and CSSCs and their successful transplantation have been described and tested in several preclinical studies and clinical trials. This review describes in detail phenotypic characteristics of LESCs and CSSCs and discusses their therapeutic potential in corneal regeneration. Since efficient and safe corneal stem cell-based therapy is still a challenging issue that requires continuous cooperation between researchers, clinicians, and patients, this review addresses the important limitations and suggests possible strategies for improvement of corneal stem cell-based therapy.
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