Carbamazepine (CBZ) is widely used in the control of convulsive crisis, treatment of trigeminal neuralgia and affective disorders. This drug has been administered to pregnant women to prevent seizures, and this antiepileptic drug (AED) treatment cannot be discontinued because of the risk of seizures during pregnancy, which can be harmful to both mother and child (Pennell, 2013). CBZ crosses the placental barrier, reaching the embryo/foetus. The use of CBZ during gestation is associated with a twofold or threefold increase in the occurrence of congenital malformations (Matalon, Schechtman, Goldzweig, & Ornoy, 2002). Also, CBZ inhibits testicular steroidogenesis, directly interfering in monooxygenase activities of cytochromes P-450 and affecting androgen-dependent processes (Kühn-Velter, Herzog, &
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