ABSTRACT Introduction: Mineral and bone disorders (MBD) are major complications of chronic kidney disease (CKD)-related adverse outcomes. The Brazilian Registry of Bone Biopsy (REBRABO) is an electronic database that includes renal osteodystrophy (RO) data. We aimed to describe the epidemiological profile of RO in a sample of CKD-MBD Brazilian patients and understand its relationship with outcomes. Methods: Between August 2015 and March 2018, 260 CKD-MBD stage 3-5D patients who underwent bone biopsy were followed for 12 to 30 months. Clinical-demographic, laboratory, and histological data were analyzed. Bone fractures, hospitalizations, and death were considered the primary outcomes. Results: Osteitis fibrosa, mixed uremic osteodystrophy, adynamic bone disease, osteomalacia, osteoporosis, and aluminum (Al) accumulation were detected in 85, 43, 27, 10, 77, and 65 patients, respectively. The logistic regression showed that dialysis vintage was an independent predictor of osteoporosis (OR: 1.005; CI: 1.001-1.010; p = 0.01). The multivariate logistic regression revealed that hemodialysis treatment (OR: 11.24; CI: 1.227-100; p = 0.03), previous parathyroidectomy (OR: 4.97; CI: 1.422-17.241; p = 0.01), and female gender (OR: 2.88; CI: 1.080-7.679; p = 0.03) were independent predictors of Al accumulation; 115 patients were followed for 21 ± 5 months. There were 56 hospitalizations, 14 deaths, and 7 fractures during follow-up. The COX regression revealed that none of the variable related to the RO/turnover, mineralization and volume (TMV) classification was an independent predictor of the outcomes. Conclusion: Hospitalization or death was not influenced by the type of RO, Al accumulation, or TMV classification. An elevated prevalence of osteoporosis and Al accumulation was detected.

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Resumo A doença cardiovascular (DCV) é a principal causa de mortalidade em pacientes com doença renal crônica (DRC). A sarcopenia, por sua vez, é prevalente nesse grupo de pacientes e está associada à ocorrência de complicações cardiovasculares. Os produtos da glicação avançada (AGEs), tipos de toxinas urêmicas, parecem estar relacionados à sarcopenia. Recentemente foi desenvolvida uma técnica não invasiva para avaliar a deposição tecidual de AGEs através da autofluorescência da pele (AF). Objetivo: quantificar AGEs através de AF da pele em pacientes com DRC em diálise peritoneal e estabelecer relações com parâmetros clínicos, bioquímicos, de DCV e de sarcopenia.

Objetivo: Analisar a distribuição sazonal e espacial dos traumas, aliados à avaliação das características das vítimas envolvidas e os tipos de chamadas relacionadas ao trauma. Materiais e Métodos: As informações foram colhidas a partir do banco de dados do corpo de bombeiros de Itajubá (9ºBBM) referentes ao período de 1 de janeiro de 2003 à 31 de dezembro de 2010 (n=51536). Resultados: O número de traumas corresponde a 11% (n=5092) do total de atendimentos realizados no período estudado, sendo os acidentes de trânsito os principais responsáveis pelas ocorrências (55%). O sexo masculino na faixa etária de 30-50 anos é o perfil mais característico das vítimas, e o final da tarde o período com maior concentração de traumas. Em relação a distribuição semanal, o final de semana possui a grande maioria das ocorrências e o mês de junho é ligeiramente o mais acometido. Conclusão: Esse conhecimento detalhado das vítimas pode repercutir na melhora e no direcionamento do Atendimento Pré-Hospitalar (APH), tanto na fase pré, quanto intra-hospitalar, além de subsidiar decisões estratégicas na gestão do trânsito e da saúde pública.Palavras-chave: Trauma, Bombeiro, Atendimento Pré-HospitalarABSTRACTObjective: To evaluate the seasonal and spatial distribution of the traumas, together with   the analysis of the characteristics of the victims and the kind of call related to the trauma. Materials and Methods: The information was collected from the database of the firefighters corporation of  Itajubá (9ºBBM) referring to the period from January 1st, 2003 to December 31st, 2010 (n= 51536). Results: The number of traumas correspond to 11% (n=5092) of total calls. Traffic accidents were the biggest causes for the occurrences (55%). Individuals predominantly from the masculine gender, 30-50 years old is the profile that mostly characterized the victims, and the end of the afternoon is the period with the biggest concentration of traumas. Conclusion: Knowing the profile of victims could have an effect on improving care and directing treatment in the Pre- Hospital Attendance (PHA)  both pre and intra-hospital, in addition to supporting strategic decisions on traffic management and public health.Keywords: Trauma, Firefighter, Pre-hospital Attendance