Coronavirus disease-2019 (COVID-19) is a global pandemic health problem that causes a wide spectrum of clinical manifestations. Recovered patients who survive COVID-19 may continue to report a wide variety of clinical manifestations such as depression, which is named post covid syndrome. In our article, we sought to determine the frequency and possible causes of depressive symptoms and clinically-significant depression in the post COVID syndrome. We conducted a review of postcovid manifestations by searching PubMed, Scopus, World health organization (WHO) databases. The symptoms of postcovid syndrome have been shown as a weakness, cognitive impairment, sleep disturbance, and depression, among others. Persistent mental disorders among people who suffer from long-term COVID-19 may be related to psychological factors, as well as from infection and the associated neurobiological trauma. According to available studies, a significant percentage of depression symptoms is observed among people with postcovid syndrome, especially in older age groups. Also symptoms of mental, neurological and physical illness as well as inflammatory brain injury in people with post-COVID syndrome are likely to increase suicidal ideation and behavior in this patient population.

Home hemodialysis (HHD) is a discovery from 1961 that is now experiencing a revival. It is a convenient and modern method of renal replacement therapy that allows the patient to undergo hemodialysis sessions at home. Due to the growing interest in home hemodialysis, we decided to present the potential of this renal replacement method, show both its benefits and complications resulting from its use. Undoubtedly, HHD has many benefits resulting mainly from the possibility of regulating the duration of the sessions and increasing their frequency. However, this method is also burdened with numerous complications. There are training courses in the use of HHD for patients who have just been diagnosed with end-stage renal disease as well as for patients undergoing dialysis using other methods. Appropriate patient selection is an important factor for the success of home therapy. There is a fierce battle in the home hemodialysis machine market. Manufacturers are outdoing each other in innovative technologies to ensure ease of use, trouble-free operation and minimize complications. The costs of home hemodialysis include more components than the dialysis treatment itself. Home hemodialysis gives patients comfort and independence above all. This is part of nephrology that undoubtedly requires a lot of work and development, but is certainly an invention of the 21st century.

Arystolocholic acid nephropathy is chronic kidney disease caused by the use of substances of natural origin that contain arystolocholic acid. The effects of their use are arystolochic acid nephropathies, which include "Chinese Herbs" nephropathy. The course of the disease is very fast, resulting in progression to end-stage renal disease, and in the future it results in the development of urinary tract cancer. That is why it is so important to recognize it early and start treatment. However, due to disease progression, some patients require dialysis and even kidney transplantation. Although the World Health Organization is trying to stop the spread of the use of harmful substances, there are still reports of this nephropathy appearing in some populations. Despite warnings from the Food and Drug Administration regarding the safety of botanicals containing arystolochic acid and its classification as a human carcinogen, products containing it are still available for purchase online. The purpose of the literature review below is to analyze the latest knowledge on aristolochic acid nephropathy and its associated complication.

INTRODUCTION: Chronic Kidney Disease (CKD) is a condition affecting nearly 16% of the population. It is a disease that cannot be completely cured with modern medical capabilities. However, it is possible to halt the progression of the disease and postpone renal replacement therapy through pharmacotherapy. In order to monitor the progression of the disease, GFR should be determined.        PURPOSE OF THE WORK: This article reviews the potential impact of typical Western diet and eating habits on the occurrence and progression of chronic kidney disease. Reducing the intake of animal protein, foods rich in sodium potassium and phosphorus, and increasing the intake of fruits, vegetables and fiber help prevent or delay end-stage renal disease. The literature on the role of a low-protein plant-based diet in patients with CKD was also reviewed.        DESCRIPTION OF THE STATE OF KNOWLEDGE: In addition to pharmacological methods, whose main goal is to reduce proteinuria and control blood pressure, drug therapy can be supported by non-pharmacological methods. One of them is the use of a low-protein diet and adequate provision of macro- and micronutrients in the diet.         SUMMARY: In order to support pharmacotherapy in the treatment of chronic kidney disease, the use of an appropriate diet plays an important role. According to the literature, the most important is restriction of protein supply, weight reduction in obese patients and supplementation of micronutrient deficiencies that occur.