Background: Vitamin A (all-trans-retinol) derivatives are collectively referred to as retinoids. It is FDA approved to treat acne. We aimed to assess the prevalence, knowledge, attitude, and practice of using topical retinoids among all the region's populations. Methods: A cross-sectional study was carried out in all Saudi Arabian regions from October 2021 to November 2021 through a verified electronic-based self-administered questionnaire. Results: The survey questionnaire was completed by a total of 1,139 people. In Saudi Arabia, the frequency of acne among males and females is approximately 73.2 percent. The subject's knowledge of topical retinoids contraindicates is spread out between 44.6 percent and 77.5 percent. Approximately half of the study participants took topical retinoids without a prescription. Conclusion: In this study, the most commonly reported effect after using topical retinoids was a reduction in acne formation. This indicates that topical retinoids have a very good effect in the treatment of acne. The other preferable outcomes to use retinoids include preventing wrinkles and facial lines, as well as enhancing skin brightness. The majority did not seek a medical prescription for topical retinoids and did not utilize them properly, which lowered their satisfaction with the benefits of topical retinoids.

In the different healthcare settings, evidence shows that healthcare workers can be exposed to various work-related hazards, which might be ergonomics, biological, psychological, and physical hazards. Work-related musculoskeletal disorders are frequently reported among the different healthcare workers, and estimates indicate that surgeons are the most commonly affected. Disorders and injuries related to the backbone, shoulders, wrist, and knees are mainly reported by healthcare workers as relevant ergonomic hazards. In the present literature review, we have discussed the commonest ergonomics that have been reported in the literature among healthcare workers. Musculoskeletal disorders as back, knee, and wrist pain are the most frequently reported among the different settings. We have also assessed the different reasons that might attribute to the development of such events, and increased workload and working hours, in addition to the harmful postures are the main reasons that have been reported in the literature. Each clinical and surgical setting might be associated with significant risk factors over others, and therefore, specific interventions should be applied within these settings to enhance satisfaction among healthcare workers. Healthcare authorities are mainly responsible to achieve this. However, further epidemiological investigations are still needed to adequately plan the righteous interventional programs.